CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Sfold - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Sfold & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Sfold RNASLOpt
MCC 0.383 > 0.000
Average MCC ± 95% Confidence Intervals 0.383 ± > 0.000 ±
Sensitivity 0.308 > 0.000
Positive Predictive Value 0.476 > 0.000
Total TP 80 > 0
Total TN 456322 < 456490
Total FP 102 > 0
Total FP CONTRA 10 > 0
Total FP INCONS 78 > 0
Total FP COMP 14 > 0
Total FN 180 < 260
P-value 0.0

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Performance plots


  1. Comparison of performance of Sfold and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Sfold and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Sfold and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Sfold and RNASLOpt).

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Performance of Sfold - scored higher in this pairwise comparison

1. Total counts & total scores for Sfold

Total Base Pair Counts
Total TP 80
Total TN 456322
Total FP 102
Total FP CONTRA 10
Total FP INCONS 78
Total FP COMP 14
Total FN 180
Total Scores
MCC 0.383
Average MCC ± 95% Confidence Intervals 0.383 ±
Sensitivity 0.308
Positive Predictive Value 0.476
Nr of predictions 1

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2. Individual counts for Sfold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.38 0.31 0.48 80 456322 102 10 78 14 180

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 0
Total TN 456490
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 260
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ±
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 1

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
CRW_00443 - 0.00 0.00 0.00 0 456490 0 0 0 0 260

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.