CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of PPfold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & PPfold(seed) [.zip] - may take several seconds...


Overview

Metric CMfinder(20) PPfold(seed)
MCC 0.652 > 0.000
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224 > 0.000 ± 0.000
Sensitivity 0.518 > 0.000
Positive Predictive Value 0.831 > 0.000
Total TP 59 > 0
Total TN 8166 < 8237
Total FP 16 > 0
Total FP CONTRA 3 > 0
Total FP INCONS 9 > 0
Total FP COMP 4 > 0
Total FN 55 < 114
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CMfinder(20) and PPfold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and PPfold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and PPfold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and PPfold(seed)).

^top





Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 59
Total TN 8166
Total FP 16
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 4
Total FN 55
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224
Sensitivity 0.518
Positive Predictive Value 0.831
Nr of predictions 4

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J2L_3 0.57 0.50 0.65 17 2994 11 2 7 2 17
3ZEX_D 0.70 0.54 0.90 19 2775 3 0 2 1 16
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

^top



Performance of PPfold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(seed)

Total Base Pair Counts
Total TP 0
Total TN 8237
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 114
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 4

^top



2. Individual counts for PPfold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.00 0.00 0.00 0 1219 0 0 0 0 21
3J2L_3 0.00 0.00 0.00 0 3020 0 0 0 0 34
3ZEX_D 0.00 0.00 0.00 0 2796 0 0 0 0 35
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.