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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of Vsfold5 - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & Vsfold5 [.zip] - may take several seconds...


Overview

Metric CMfinder(20) Vsfold5
MCC 0.652 > 0.522
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224 > 0.538 ± 0.485
Sensitivity 0.518 > 0.500
Positive Predictive Value 0.831 > 0.559
Total TP 59 > 57
Total TN 8166 > 8135
Total FP 16 < 51
Total FP CONTRA 3 < 14
Total FP INCONS 9 < 31
Total FP COMP 4 < 6
Total FN 55 < 57
P-value 0.0

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Performance plots


  1. Comparison of performance of CMfinder(20) and Vsfold5. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and Vsfold5).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and Vsfold5. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and Vsfold5).

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Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 59
Total TN 8166
Total FP 16
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 4
Total FN 55
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224
Sensitivity 0.518
Positive Predictive Value 0.831
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J2L_3 0.57 0.50 0.65 17 2994 11 2 7 2 17
3ZEX_D 0.70 0.54 0.90 19 2775 3 0 2 1 16
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Performance of Vsfold5 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold5

Total Base Pair Counts
Total TP 57
Total TN 8135
Total FP 51
Total FP CONTRA 14
Total FP INCONS 31
Total FP COMP 6
Total FN 57
Total Scores
MCC 0.522
Average MCC ± 95% Confidence Intervals 0.538 ± 0.485
Sensitivity 0.500
Positive Predictive Value 0.559
Nr of predictions 4

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2. Individual counts for Vsfold5 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.76 0.76 0.76 16 1198 6 3 2 1 5
3J2L_3 0.70 0.71 0.71 24 2986 13 3 7 3 10
3ZEX_D 0.09 0.09 0.12 3 2771 24 5 17 2 32
4FRG_B 0.60 0.58 0.64 14 1180 8 3 5 0 10

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.