CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of Carnac(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & Carnac(20) [.zip] - may take several seconds...


Overview

Metric CRWrnafold Carnac(20)
MCC 0.668 > 0.620
Average MCC ± 95% Confidence Intervals 0.692 ± 0.219 > 0.473 ± 0.321
Sensitivity 0.683 > 0.470
Positive Predictive Value 0.663 < 0.828
Total TP 112 > 77
Total TN 12205 < 12281
Total FP 83 > 22
Total FP CONTRA 18 > 2
Total FP INCONS 39 > 14
Total FP COMP 26 > 6
Total FN 52 < 87
P-value 0.0

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Performance plots


  1. Comparison of performance of CRWrnafold and Carnac(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and Carnac(20)).

  2. Comparison of performance of CRWrnafold and Carnac(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and Carnac(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and Carnac(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and Carnac(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and Carnac(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and Carnac(20)).

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Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 112
Total TN 12205
Total FP 83
Total FP CONTRA 18
Total FP INCONS 39
Total FP COMP 26
Total FN 52
Total Scores
MCC 0.668
Average MCC ± 95% Confidence Intervals 0.692 ± 0.219
Sensitivity 0.683
Positive Predictive Value 0.663
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.77 0.79 0.75 15 1137 8 0 5 3 4
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_3 0.85 0.84 0.86 31 2727 7 0 5 2 6
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Performance of Carnac(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(20)

Total Base Pair Counts
Total TP 77
Total TN 12281
Total FP 22
Total FP CONTRA 2
Total FP INCONS 14
Total FP COMP 6
Total FN 87
Total Scores
MCC 0.620
Average MCC ± 95% Confidence Intervals 0.473 ± 0.321
Sensitivity 0.470
Positive Predictive Value 0.828
Nr of predictions 7

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2. Individual counts for Carnac(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.79 0.79 0.79 15 1138 7 0 4 3 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4A1C_2 0.42 0.25 0.71 5 4509 3 0 2 1 15
4AOB_A 0.59 0.48 0.74 14 1418 6 2 3 1 15
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.