CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric CRWrnafold Carnac(seed)
MCC 0.588 > 0.156
Average MCC ± 95% Confidence Intervals 0.578 ± 0.330 > 0.066 ± 0.163
Sensitivity 0.595 > 0.025
Positive Predictive Value 0.591 < 1.000
Total TP 97 > 4
Total TN 11581 < 11741
Total FP 90 > 0
Total FP CONTRA 21 > 0
Total FP INCONS 46 > 0
Total FP COMP 23 > 0
Total FN 66 < 159
P-value 0.0

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Performance plots


  1. Comparison of performance of CRWrnafold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and Carnac(seed)).

  2. Comparison of performance of CRWrnafold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and Carnac(seed)).

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Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 97
Total TN 11581
Total FP 90
Total FP CONTRA 21
Total FP INCONS 46
Total FP COMP 23
Total FN 66
Total Scores
MCC 0.588
Average MCC ± 95% Confidence Intervals 0.578 ± 0.330
Sensitivity 0.595
Positive Predictive Value 0.591
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_3 0.85 0.84 0.86 31 2727 7 0 5 2 6
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 11741
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 159
Total Scores
MCC 0.156
Average MCC ± 95% Confidence Intervals 0.066 ± 0.163
Sensitivity 0.025
Positive Predictive Value 1.000
Nr of predictions 7

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.