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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CRWrnafold - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for CRWrnafold & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric CRWrnafold TurboFold(seed)
MCC 0.588 > 0.580
Average MCC ± 95% Confidence Intervals 0.578 ± 0.330 > 0.558 ± 0.310
Sensitivity 0.595 > 0.558
Positive Predictive Value 0.591 < 0.615
Total TP 97 > 91
Total TN 11581 < 11597
Total FP 90 > 72
Total FP CONTRA 21 > 17
Total FP INCONS 46 > 40
Total FP COMP 23 > 15
Total FN 66 < 72
P-value 0.0

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Performance plots


  1. Comparison of performance of CRWrnafold and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CRWrnafold and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CRWrnafold and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CRWrnafold and TurboFold(seed)).

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Performance of CRWrnafold - scored higher in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 97
Total TN 11581
Total FP 90
Total FP CONTRA 21
Total FP INCONS 46
Total FP COMP 23
Total FN 66
Total Scores
MCC 0.588
Average MCC ± 95% Confidence Intervals 0.578 ± 0.330
Sensitivity 0.595
Positive Predictive Value 0.591
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_3 0.85 0.84 0.86 31 2727 7 0 5 2 6
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 91
Total TN 11597
Total FP 72
Total FP CONTRA 17
Total FP INCONS 40
Total FP COMP 15
Total FN 72
Total Scores
MCC 0.580
Average MCC ± 95% Confidence Intervals 0.558 ± 0.310
Sensitivity 0.558
Positive Predictive Value 0.615
Nr of predictions 7

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.