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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Carnac(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Carnac(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric Carnac(20) CMfinder(20)
MCC 0.654 > 0.652
Average MCC ± 95% Confidence Intervals 0.647 ± 0.214 < 0.662 ± 0.224
Sensitivity 0.544 > 0.518
Positive Predictive Value 0.795 < 0.831
Total TP 62 > 59
Total TN 8159 < 8166
Total FP 22 > 16
Total FP CONTRA 1 < 3
Total FP INCONS 15 > 9
Total FP COMP 6 > 4
Total FN 52 < 55
P-value 0.0

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Performance plots


  1. Comparison of performance of Carnac(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Carnac(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Carnac(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Carnac(20) and CMfinder(20)).

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Performance of Carnac(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Carnac(20)

Total Base Pair Counts
Total TP 62
Total TN 8159
Total FP 22
Total FP CONTRA 1
Total FP INCONS 15
Total FP COMP 6
Total FN 52
Total Scores
MCC 0.654
Average MCC ± 95% Confidence Intervals 0.647 ± 0.214
Sensitivity 0.544
Positive Predictive Value 0.795
Nr of predictions 4

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2. Individual counts for Carnac(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.69 0.71 0.68 15 1197 8 1 6 1 6
3J2L_3 0.59 0.53 0.67 18 2993 11 0 9 2 16
3ZEX_D 0.81 0.66 1.00 23 2773 3 0 0 3 12
4FRG_B 0.50 0.25 1.00 6 1196 0 0 0 0 18

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 59
Total TN 8166
Total FP 16
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 4
Total FN 55
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224
Sensitivity 0.518
Positive Predictive Value 0.831
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J2L_3 0.57 0.50 0.65 17 2994 11 2 7 2 17
3ZEX_D 0.70 0.54 0.90 19 2775 3 0 2 1 16
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.