CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Multilign(seed)
MCC 0.601 > 0.554
Average MCC ± 95% Confidence Intervals 0.587 ± 0.227 > 0.478 ± 0.465
Sensitivity 0.569 > 0.489
Positive Predictive Value 0.645 > 0.638
Total TP 78 > 67
Total TN 11055 < 11071
Total FP 55 > 41
Total FP CONTRA 12 > 8
Total FP INCONS 31 > 30
Total FP COMP 12 > 3
Total FN 59 < 70
P-value 0.0

^top




Performance plots


  1. Comparison of performance of ContextFold and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Multilign(seed)).

^top





Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 78
Total TN 11055
Total FP 55
Total FP CONTRA 12
Total FP INCONS 31
Total FP COMP 12
Total FN 59
Total Scores
MCC 0.601
Average MCC ± 95% Confidence Intervals 0.587 ± 0.227
Sensitivity 0.569
Positive Predictive Value 0.645
Nr of predictions 5

^top



2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
3W3S_B 0.87 0.85 0.90 28 1958 4 0 3 1 5
3ZEX_C 0.44 0.41 0.48 12 5349 23 4 9 10 17
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4FRN_A 0.42 0.39 0.46 11 1824 13 6 7 0 17

^top



Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 67
Total TN 11071
Total FP 41
Total FP CONTRA 8
Total FP INCONS 30
Total FP COMP 3
Total FN 70
Total Scores
MCC 0.554
Average MCC ± 95% Confidence Intervals 0.478 ± 0.465
Sensitivity 0.489
Positive Predictive Value 0.638
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3W3S_B 0.92 0.88 0.97 29 1959 2 0 1 1 4
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10
4FRN_A 0.27 0.21 0.35 6 1831 11 2 9 0 22

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.