CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold RNASampler(seed)
MCC 0.577 > 0.371
Average MCC ± 95% Confidence Intervals 0.538 ± 0.411 > 0.341 ± 0.418
Sensitivity 0.550 > 0.290
Positive Predictive Value 0.611 > 0.483
Total TP 55 > 29
Total TN 12317 < 12347
Total FP 59 > 45
Total FP CONTRA 7 > 6
Total FP INCONS 28 > 25
Total FP COMP 24 > 14
Total FN 45 < 71
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and RNASampler(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 55
Total TN 12317
Total FP 59
Total FP CONTRA 7
Total FP INCONS 28
Total FP COMP 24
Total FN 45
Total Scores
MCC 0.577
Average MCC ± 95% Confidence Intervals 0.538 ± 0.411
Sensitivity 0.550
Positive Predictive Value 0.611
Nr of predictions 4

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
3W3S_B 0.87 0.85 0.90 28 1958 4 0 3 1 5
3ZEX_C 0.44 0.41 0.48 12 5349 23 4 9 10 17
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 29
Total TN 12347
Total FP 45
Total FP CONTRA 6
Total FP INCONS 25
Total FP COMP 14
Total FN 71
Total Scores
MCC 0.371
Average MCC ± 95% Confidence Intervals 0.341 ± 0.418
Sensitivity 0.290
Positive Predictive Value 0.483
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3W3S_B 0.60 0.36 1.00 12 1977 1 0 0 1 21
3ZEX_C 0.39 0.31 0.50 9 5356 14 2 7 5 20
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.