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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of TurboFold(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & TurboFold(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold TurboFold(seed)
MCC 0.606 > 0.576
Average MCC ± 95% Confidence Intervals 0.597 ± 0.187 > 0.559 ± 0.266
Sensitivity 0.560 > 0.545
Positive Predictive Value 0.665 > 0.619
Total TP 107 > 104
Total TN 17273 > 17266
Total FP 79 < 83
Total FP CONTRA 16 < 18
Total FP INCONS 38 < 46
Total FP COMP 25 > 19
Total FN 84 < 87
P-value 0.0

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Performance plots


  1. Comparison of performance of ContextFold and TurboFold(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and TurboFold(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and TurboFold(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and TurboFold(seed)).

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Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 107
Total TN 17273
Total FP 79
Total FP CONTRA 16
Total FP INCONS 38
Total FP COMP 25
Total FN 84
Total Scores
MCC 0.606
Average MCC ± 95% Confidence Intervals 0.597 ± 0.187
Sensitivity 0.560
Positive Predictive Value 0.665
Nr of predictions 8

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2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.58 0.56 0.63 10 512 6 0 6 0 8
3ZEX_C 0.44 0.41 0.48 12 5349 23 4 9 10 17
4A1C_3 0.96 0.92 1.00 34 2729 1 0 0 1 3
4A1C_2 0.26 0.25 0.28 5 4498 26 3 10 13 15
4AOB_A 0.62 0.59 0.68 17 1412 9 2 6 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6
4FRN_A 0.42 0.39 0.46 11 1824 13 6 7 0 17

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Performance of TurboFold(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 104
Total TN 17266
Total FP 83
Total FP CONTRA 18
Total FP INCONS 46
Total FP COMP 19
Total FN 87
Total Scores
MCC 0.576
Average MCC ± 95% Confidence Intervals 0.559 ± 0.266
Sensitivity 0.545
Positive Predictive Value 0.619
Nr of predictions 8

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6
4FRN_A 0.79 0.71 0.87 20 1825 3 1 2 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.