CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Cylofold - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Cylofold & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Cylofold Carnac(seed)
MCC 0.684 > 0.216
Average MCC ± 95% Confidence Intervals 0.704 ± 0.144 > 0.081 ± 0.126
Sensitivity 0.662 > 0.047
Positive Predictive Value 0.716 < 1.000
Total TP 307 > 22
Total TN 30731 < 31138
Total FP 154 > 1
Total FP CONTRA 36 > 0
Total FP INCONS 86 > 0
Total FP COMP 32 > 1
Total FN 157 < 442
P-value 3.66763272401e-08

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Performance plots


  1. Comparison of performance of Cylofold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and Carnac(seed)).

  2. Comparison of performance of Cylofold and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Cylofold and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for Cylofold and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Cylofold and Carnac(seed)).

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Performance of Cylofold - scored higher in this pairwise comparison

1. Total counts & total scores for Cylofold

Total Base Pair Counts
Total TP 307
Total TN 30731
Total FP 154
Total FP CONTRA 36
Total FP INCONS 86
Total FP COMP 32
Total FN 157
Total Scores
MCC 0.684
Average MCC ± 95% Confidence Intervals 0.704 ± 0.144
Sensitivity 0.662
Positive Predictive Value 0.716
Nr of predictions 18

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2. Individual counts for Cylofold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L1F_B 0.93 0.88 1.00 21 770 0 0 0 0 3
2L1F_A 0.93 0.87 1.00 20 743 0 0 0 0 3
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
2XKV_B 0.41 0.55 0.32 6 1816 25 9 4 12 5
2XXA_G 0.10 0.11 0.11 4 2009 32 2 30 0 31
3IZF_C 0.85 0.83 0.88 29 2607 7 0 4 3 6
3O58_3 0.42 0.50 0.35 11 4733 30 9 11 10 11
3O58_2 0.90 0.84 0.96 26 2727 3 0 1 2 5
3PDR_A 0.86 0.78 0.95 39 4799 4 1 1 2 11
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3W3S_B 0.48 0.45 0.52 15 1960 15 1 13 1 18
4AOB_A 0.42 0.38 0.48 11 1414 13 3 9 1 18
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0
4FRG_B 0.93 0.88 1.00 21 1181 0 0 0 0 3
4FRN_A 0.23 0.18 0.31 5 1832 11 7 4 0 23

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 22
Total TN 31138
Total FP 1
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 1
Total FN 442
Total Scores
MCC 0.216
Average MCC ± 95% Confidence Intervals 0.081 ± 0.126
Sensitivity 0.047
Positive Predictive Value 1.000
Nr of predictions 18

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L1F_B 0.00 0.00 0.00 0 791 0 0 0 0 24
2L1F_A 0.00 0.00 0.00 0 763 0 0 0 0 23
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
2XKV_B 0.00 0.00 0.00 0 1835 0 0 0 0 11
2XXA_G 0.00 0.00 0.00 0 2045 0 0 0 0 35
3IZF_C 0.00 0.00 0.00 0 2640 0 0 0 0 35
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3O58_2 0.00 0.00 0.00 0 2754 0 0 0 0 31
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
3W3S_B 0.00 0.00 0.00 0 1989 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24
4FRN_A 0.00 0.00 0.00 0 1848 0 0 0 0 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.