CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) Mastr(20)
MCC 0.755 > 0.620
Average MCC ± 95% Confidence Intervals 0.762 ± 0.067 > 0.584 ± 0.128
Sensitivity 0.720 > 0.473
Positive Predictive Value 0.796 < 0.819
Total TP 645 > 424
Total TN 92052 < 92344
Total FP 335 > 174
Total FP CONTRA 65 > 16
Total FP INCONS 100 > 78
Total FP COMP 170 > 80
Total FN 251 < 472
P-value 3.56938820447e-08

^top




Performance plots


  1. Comparison of performance of MXScarna(20) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Mastr(20)).

  2. Comparison of performance of MXScarna(20) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and Mastr(20)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Mastr(20)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for MXScarna(20) and Mastr(20)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Mastr(20)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and Mastr(20)).

^top





Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 645
Total TN 92052
Total FP 335
Total FP CONTRA 65
Total FP INCONS 100
Total FP COMP 170
Total FN 251
Total Scores
MCC 0.755
Average MCC ± 95% Confidence Intervals 0.762 ± 0.067
Sensitivity 0.720
Positive Predictive Value 0.796
Nr of predictions 34

^top



2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 1.00 1.00 1.00 10 164 0 0 0 0 0
2L94_A 0.73 0.72 0.76 13 340 5 0 4 1 5
2WRQ_Y 1.00 1.00 1.00 9 1143 14 0 0 14 0
2XKV_B 0.60 0.36 1.00 4 1831 3 0 0 3 7
2XQD_Y 0.98 0.95 1.00 20 1109 1 0 0 1 1
2XXA_G 0.88 0.86 0.91 30 2012 4 0 3 1 5
3A2K_C 0.74 0.73 0.76 16 1087 6 1 4 1 6
3AMU_B 1.00 1.00 1.00 19 1138 3 0 0 3 0
3G4S_9 0.78 0.77 0.80 20 2711 16 2 3 11 6
3GX2_A 0.81 0.79 0.85 22 1423 6 2 2 2 6
3IVN_B 0.81 0.74 0.89 17 884 2 2 0 0 6
3IZ4_A 0.58 0.54 0.63 51 25455 35 18 12 5 44
3IZF_C 0.87 0.89 0.86 31 2604 12 0 5 7 4
3J20_0 0.93 0.90 0.95 19 1199 1 1 0 0 2
3J20_1 0.97 0.95 1.00 19 1093 1 0 0 1 1
3J2L_3 0.67 0.65 0.71 22 2989 11 3 6 2 12
3JYV_7 0.95 0.90 1.00 18 1093 2 0 0 2 2
3JYX_4 0.70 0.83 0.59 10 4739 32 5 2 25 2
3JYX_3 0.73 0.73 0.73 11 2363 26 0 4 22 4
3LA5_A 0.87 0.80 0.95 20 933 1 1 0 0 5
3NPB_A 0.77 0.73 0.82 27 2245 9 2 4 3 10
3O58_2 0.92 0.90 0.93 28 2724 13 0 2 11 3
3O58_3 0.62 0.59 0.65 13 4744 18 5 2 11 9
3PDR_A 0.85 0.82 0.89 41 4794 9 2 3 4 9
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
3ZEX_C 0.35 0.31 0.41 9 5352 15 3 10 2 20
3ZEX_D 0.85 0.83 0.88 29 2763 13 0 4 9 6
4A1C_3 0.80 0.78 0.83 29 2728 12 0 6 6 8
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8
4FRG_B 0.65 0.58 0.74 14 1183 6 2 3 1 10

^top



Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 424
Total TN 92344
Total FP 174
Total FP CONTRA 16
Total FP INCONS 78
Total FP COMP 80
Total FN 472
Total Scores
MCC 0.620
Average MCC ± 95% Confidence Intervals 0.584 ± 0.128
Sensitivity 0.473
Positive Predictive Value 0.819
Nr of predictions 34

^top



2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 1.00 1.00 1.00 10 164 0 0 0 0 0
2L94_A 0.88 0.83 0.94 15 341 2 0 1 1 3
2WRQ_Y 1.00 1.00 1.00 9 1143 13 0 0 13 0
2XKV_B 0.60 0.36 1.00 4 1831 3 0 0 3 7
2XQD_Y 0.98 0.95 1.00 20 1109 1 0 0 1 1
2XXA_G 0.44 0.20 1.00 7 2038 0 0 0 0 28
3A2K_C 0.81 0.77 0.85 17 1088 3 0 3 0 5
3AMU_B 0.89 0.79 1.00 15 1142 2 0 0 2 4
3G4S_9 0.68 0.62 0.76 16 2715 10 2 3 5 10
3GX2_A 0.46 0.39 0.55 11 1429 10 2 7 1 17
3IVN_B 0.86 0.83 0.90 19 882 2 2 0 0 4
3IZ4_A 0.00 0.00 0.00 0 25536 0 0 0 0 95
3IZF_C 0.91 0.91 0.91 32 2605 9 0 3 6 3
3J20_0 0.95 0.95 0.95 20 1198 2 1 0 1 1
3J20_1 0.26 0.25 0.29 5 1095 12 1 11 0 15
3J2L_3 0.42 0.38 0.48 13 2993 16 2 12 2 21
3JYV_7 0.97 0.95 1.00 19 1092 2 0 0 2 1
3JYX_4 0.00 0.00 0.00 0 4756 0 0 0 0 12
3JYX_3 0.77 0.80 0.75 12 2362 26 0 4 22 3
3LA5_A 0.89 0.80 1.00 20 934 0 0 0 0 5
3NPB_A 0.34 0.30 0.41 11 2251 18 1 15 2 26
3O58_2 0.93 0.94 0.94 29 2723 12 0 2 10 2
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
3ZEX_D 0.93 0.91 0.94 32 2762 7 0 2 5 3
4A1C_3 0.88 0.86 0.89 32 2727 7 0 4 3 5
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19
4ENB_A 0.44 0.20 1.00 3 469 0 0 0 0 12
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.