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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Mastr(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Mastr(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Mastr(20) Mastr(seed)
MCC 0.620 > 0.000
Average MCC ± 95% Confidence Intervals 0.584 ± 0.128 > 0.000 ± 0.000
Sensitivity 0.473 > 0.000
Positive Predictive Value 0.819 > 0.000
Total TP 424 > 0
Total TN 92344 < 92862
Total FP 174 > 0
Total FP CONTRA 16 > 0
Total FP INCONS 78 > 0
Total FP COMP 80 > 0
Total FN 472 < 896
P-value 5.23657817852e-08

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Performance plots


  1. Comparison of performance of Mastr(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  2. Comparison of performance of Mastr(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for Mastr(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Mastr(20) and Mastr(seed)).

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Performance of Mastr(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 424
Total TN 92344
Total FP 174
Total FP CONTRA 16
Total FP INCONS 78
Total FP COMP 80
Total FN 472
Total Scores
MCC 0.620
Average MCC ± 95% Confidence Intervals 0.584 ± 0.128
Sensitivity 0.473
Positive Predictive Value 0.819
Nr of predictions 34

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2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 1.00 1.00 1.00 10 164 0 0 0 0 0
2L94_A 0.88 0.83 0.94 15 341 2 0 1 1 3
2WRQ_Y 1.00 1.00 1.00 9 1143 13 0 0 13 0
2XKV_B 0.60 0.36 1.00 4 1831 3 0 0 3 7
2XQD_Y 0.98 0.95 1.00 20 1109 1 0 0 1 1
2XXA_G 0.44 0.20 1.00 7 2038 0 0 0 0 28
3A2K_C 0.81 0.77 0.85 17 1088 3 0 3 0 5
3AMU_B 0.89 0.79 1.00 15 1142 2 0 0 2 4
3G4S_9 0.68 0.62 0.76 16 2715 10 2 3 5 10
3GX2_A 0.46 0.39 0.55 11 1429 10 2 7 1 17
3IVN_B 0.86 0.83 0.90 19 882 2 2 0 0 4
3IZ4_A 0.00 0.00 0.00 0 25536 0 0 0 0 95
3IZF_C 0.91 0.91 0.91 32 2605 9 0 3 6 3
3J20_0 0.95 0.95 0.95 20 1198 2 1 0 1 1
3J20_1 0.26 0.25 0.29 5 1095 12 1 11 0 15
3J2L_3 0.42 0.38 0.48 13 2993 16 2 12 2 21
3JYV_7 0.97 0.95 1.00 19 1092 2 0 0 2 1
3JYX_4 0.00 0.00 0.00 0 4756 0 0 0 0 12
3JYX_3 0.77 0.80 0.75 12 2362 26 0 4 22 3
3LA5_A 0.89 0.80 1.00 20 934 0 0 0 0 5
3NPB_A 0.34 0.30 0.41 11 2251 18 1 15 2 26
3O58_2 0.93 0.94 0.94 29 2723 12 0 2 10 2
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
3ZEX_D 0.93 0.91 0.94 32 2762 7 0 2 5 3
4A1C_3 0.88 0.86 0.89 32 2727 7 0 4 3 5
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19
4ENB_A 0.44 0.20 1.00 3 469 0 0 0 0 12
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 92862
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 896
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 34

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.00 0.00 0.00 0 174 0 0 0 0 10
2L94_A 0.00 0.00 0.00 0 357 0 0 0 0 18
2WRQ_Y 0.00 0.00 0.00 0 1152 0 0 0 0 9
2XKV_B 0.00 0.00 0.00 0 1835 0 0 0 0 11
2XQD_Y 0.00 0.00 0.00 0 1129 0 0 0 0 21
2XXA_G 0.00 0.00 0.00 0 2045 0 0 0 0 35
3A2K_C 0.00 0.00 0.00 0 1108 0 0 0 0 22
3AMU_B 0.00 0.00 0.00 0 1157 0 0 0 0 19
3G4S_9 0.00 0.00 0.00 0 2736 0 0 0 0 26
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3IZ4_A 0.00 0.00 0.00 0 25536 0 0 0 0 95
3IZF_C 0.00 0.00 0.00 0 2640 0 0 0 0 35
3J20_0 0.00 0.00 0.00 0 1219 0 0 0 0 21
3J20_1 0.00 0.00 0.00 0 1112 0 0 0 0 20
3J2L_3 0.00 0.00 0.00 0 3020 0 0 0 0 34
3JYV_7 0.00 0.00 0.00 0 1111 0 0 0 0 20
3JYX_4 0.00 0.00 0.00 0 4756 0 0 0 0 12
3JYX_3 0.00 0.00 0.00 0 2378 0 0 0 0 15
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_2 0.00 0.00 0.00 0 2754 0 0 0 0 31
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
3ZEX_D 0.00 0.00 0.00 0 2796 0 0 0 0 35
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.