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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MaxExpect - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MaxExpect & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric MaxExpect CMfinder(20)
MCC 0.653 > 0.652
Average MCC ± 95% Confidence Intervals 0.607 ± 0.401 < 0.662 ± 0.224
Sensitivity 0.640 > 0.518
Positive Predictive Value 0.676 < 0.831
Total TP 73 > 59
Total TN 8129 < 8166
Total FP 47 > 16
Total FP CONTRA 7 > 3
Total FP INCONS 28 > 9
Total FP COMP 12 > 4
Total FN 41 < 55
P-value 0.0

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Performance plots


  1. Comparison of performance of MaxExpect and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

  2. Comparison of performance of MaxExpect and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for MaxExpect and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MaxExpect and CMfinder(20)).

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Performance of MaxExpect - scored higher in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 73
Total TN 8129
Total FP 47
Total FP CONTRA 7
Total FP INCONS 28
Total FP COMP 12
Total FN 41
Total Scores
MCC 0.653
Average MCC ± 95% Confidence Intervals 0.607 ± 0.401
Sensitivity 0.640
Positive Predictive Value 0.676
Nr of predictions 4

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2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.53 0.57 0.50 12 1195 13 2 10 1 9
3J2L_3 0.80 0.82 0.78 28 2984 12 1 7 4 6
3ZEX_D 0.82 0.77 0.87 27 2765 11 0 4 7 8
4FRG_B 0.29 0.25 0.35 6 1185 11 4 7 0 18

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 59
Total TN 8166
Total FP 16
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 4
Total FN 55
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224
Sensitivity 0.518
Positive Predictive Value 0.831
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J2L_3 0.57 0.50 0.65 17 2994 11 2 7 2 17
3ZEX_D 0.70 0.54 0.90 19 2775 3 0 2 1 16
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.