CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Mastr(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Mastr(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Mastr(20)
MCC 0.732 > 0.616
Average MCC ± 95% Confidence Intervals 0.755 ± 0.236 > 0.573 ± 0.457
Sensitivity 0.682 > 0.488
Positive Predictive Value 0.793 > 0.788
Total TP 88 > 63
Total TN 9456 < 9487
Total FP 25 > 19
Total FP CONTRA 8 > 5
Total FP INCONS 15 > 12
Total FP COMP 2 = 2
Total FN 41 < 66
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

  2. Comparison of performance of Multilign(seed) and Mastr(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Mastr(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Mastr(20)).

^top





Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 88
Total TN 9456
Total FP 25
Total FP CONTRA 8
Total FP INCONS 15
Total FP COMP 2
Total FN 41
Total Scores
MCC 0.732
Average MCC ± 95% Confidence Intervals 0.755 ± 0.236
Sensitivity 0.682
Positive Predictive Value 0.793
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

^top



Performance of Mastr(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(20)

Total Base Pair Counts
Total TP 63
Total TN 9487
Total FP 19
Total FP CONTRA 5
Total FP INCONS 12
Total FP COMP 2
Total FN 66
Total Scores
MCC 0.616
Average MCC ± 95% Confidence Intervals 0.573 ± 0.457
Sensitivity 0.488
Positive Predictive Value 0.788
Nr of predictions 5

^top



2. Individual counts for Mastr(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.88 0.83 0.94 15 341 2 0 1 1 3
3RKF_A 0.84 0.71 1.00 17 849 0 0 0 0 7
3SD1_A 0.73 0.72 0.75 21 1505 7 4 3 0 8
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4AOB_A 0.42 0.34 0.53 10 1418 10 1 8 1 19

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.