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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RNASLOpt - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RNASLOpt [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RNASLOpt
MCC 0.554 > 0.454
Average MCC ± 95% Confidence Intervals 0.478 ± 0.465 > 0.442 ± 0.346
Sensitivity 0.489 > 0.423
Positive Predictive Value 0.638 > 0.500
Total TP 67 > 58
Total TN 11071 > 11060
Total FP 41 < 73
Total FP CONTRA 8 < 17
Total FP INCONS 30 < 41
Total FP COMP 3 < 15
Total FN 70 < 79
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and RNASLOpt. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RNASLOpt).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RNASLOpt. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RNASLOpt).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 67
Total TN 11071
Total FP 41
Total FP CONTRA 8
Total FP INCONS 30
Total FP COMP 3
Total FN 70
Total Scores
MCC 0.554
Average MCC ± 95% Confidence Intervals 0.478 ± 0.465
Sensitivity 0.489
Positive Predictive Value 0.638
Nr of predictions 5

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3W3S_B 0.92 0.88 0.97 29 1959 2 0 1 1 4
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10
4FRN_A 0.27 0.21 0.35 6 1831 11 2 9 0 22

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Performance of RNASLOpt - scored lower in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 58
Total TN 11060
Total FP 73
Total FP CONTRA 17
Total FP INCONS 41
Total FP COMP 15
Total FN 79
Total Scores
MCC 0.454
Average MCC ± 95% Confidence Intervals 0.442 ± 0.346
Sensitivity 0.423
Positive Predictive Value 0.500
Nr of predictions 5

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
3W3S_B 0.90 0.85 0.97 28 1960 2 0 1 1 5
3ZEX_C 0.32 0.34 0.31 10 5342 36 8 14 14 19
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4FRN_A 0.19 0.18 0.22 5 1825 18 6 12 0 23

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.