CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RNASampler(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RNASampler(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RNASampler(20)
MCC 0.732 > 0.720
Average MCC ± 95% Confidence Intervals 0.755 ± 0.236 > 0.741 ± 0.299
Sensitivity 0.682 > 0.643
Positive Predictive Value 0.793 < 0.814
Total TP 88 > 83
Total TN 9456 < 9465
Total FP 25 < 28
Total FP CONTRA 8 > 3
Total FP INCONS 15 < 16
Total FP COMP 2 < 9
Total FN 41 < 46
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Multilign(seed) and RNASampler(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RNASampler(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RNASampler(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RNASampler(20)).

^top





Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 88
Total TN 9456
Total FP 25
Total FP CONTRA 8
Total FP INCONS 15
Total FP COMP 2
Total FN 41
Total Scores
MCC 0.732
Average MCC ± 95% Confidence Intervals 0.755 ± 0.236
Sensitivity 0.682
Positive Predictive Value 0.793
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

^top



Performance of RNASampler(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(20)

Total Base Pair Counts
Total TP 83
Total TN 9465
Total FP 28
Total FP CONTRA 3
Total FP INCONS 16
Total FP COMP 9
Total FN 46
Total Scores
MCC 0.720
Average MCC ± 95% Confidence Intervals 0.741 ± 0.299
Sensitivity 0.643
Positive Predictive Value 0.814
Nr of predictions 5

^top



2. Individual counts for RNASampler(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.81 0.69 0.95 20 1512 1 0 1 0 9
3ZEX_C 0.35 0.31 0.39 9 5351 21 3 11 7 20
4AOB_A 0.70 0.59 0.85 17 1417 4 0 3 1 12

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.