CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RNASampler(seed)
MCC 0.696 > 0.577
Average MCC ± 95% Confidence Intervals 0.656 ± 0.400 > 0.549 ± 0.345
Sensitivity 0.649 > 0.444
Positive Predictive Value 0.754 < 0.761
Total TP 98 > 67
Total TN 10517 < 10559
Total FP 34 > 28
Total FP CONTRA 9 > 2
Total FP INCONS 23 > 19
Total FP COMP 2 < 7
Total FN 53 < 84
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RNASampler(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RNASampler(seed)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 98
Total TN 10517
Total FP 34
Total FP CONTRA 9
Total FP INCONS 23
Total FP COMP 2
Total FN 53
Total Scores
MCC 0.696
Average MCC ± 95% Confidence Intervals 0.656 ± 0.400
Sensitivity 0.649
Positive Predictive Value 0.754
Nr of predictions 6

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3W3S_B 0.92 0.88 0.97 29 1959 2 0 1 1 4
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 67
Total TN 10559
Total FP 28
Total FP CONTRA 2
Total FP INCONS 19
Total FP COMP 7
Total FN 84
Total Scores
MCC 0.577
Average MCC ± 95% Confidence Intervals 0.549 ± 0.345
Sensitivity 0.444
Positive Predictive Value 0.761
Nr of predictions 6

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
3W3S_B 0.60 0.36 1.00 12 1977 1 0 0 1 21
3ZEX_C 0.39 0.31 0.50 9 5356 14 2 7 5 20

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.