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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of RSpredict(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & RSpredict(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) RSpredict(20)
MCC 0.669 > 0.523
Average MCC ± 95% Confidence Intervals 0.660 ± 0.301 > 0.486 ± 0.358
Sensitivity 0.632 > 0.486
Positive Predictive Value 0.717 > 0.574
Total TP 91 > 70
Total TN 12182 < 12187
Total FP 38 < 58
Total FP CONTRA 16 > 15
Total FP INCONS 20 < 37
Total FP COMP 2 < 6
Total FN 53 < 74
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and RSpredict(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and RSpredict(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and RSpredict(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and RSpredict(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 91
Total TN 12182
Total FP 38
Total FP CONTRA 16
Total FP INCONS 20
Total FP COMP 2
Total FN 53
Total Scores
MCC 0.669
Average MCC ± 95% Confidence Intervals 0.660 ± 0.301
Sensitivity 0.632
Positive Predictive Value 0.717
Nr of predictions 6

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
3J3E_8 0.19 0.20 0.19 3 2726 13 8 5 0 12
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of RSpredict(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RSpredict(20)

Total Base Pair Counts
Total TP 70
Total TN 12187
Total FP 58
Total FP CONTRA 15
Total FP INCONS 37
Total FP COMP 6
Total FN 74
Total Scores
MCC 0.523
Average MCC ± 95% Confidence Intervals 0.486 ± 0.358
Sensitivity 0.486
Positive Predictive Value 0.574
Nr of predictions 6

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2. Individual counts for RSpredict(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.53 0.50 0.60 9 342 7 0 6 1 9
3J3E_8 -0.01 0.00 0.00 0 2724 19 5 13 1 15
3RKF_A 0.91 0.88 0.95 21 844 1 1 0 0 3
3SD1_A 0.82 0.86 0.78 25 1501 7 5 2 0 4
3ZEX_C 0.34 0.31 0.38 9 5350 19 3 12 4 20
4AOB_A 0.33 0.21 0.55 6 1426 5 1 4 0 23

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.