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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of TurboFold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & TurboFold(20) [.zip] - may take several seconds...


Overview

Metric Multilign(seed) TurboFold(20)
MCC 0.732 > 0.724
Average MCC ± 95% Confidence Intervals 0.755 ± 0.236 > 0.744 ± 0.231
Sensitivity 0.682 > 0.674
Positive Predictive Value 0.793 > 0.784
Total TP 88 > 87
Total TN 9456 = 9456
Total FP 25 < 30
Total FP CONTRA 8 > 6
Total FP INCONS 15 < 18
Total FP COMP 2 < 6
Total FN 41 < 42
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and TurboFold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and TurboFold(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and TurboFold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and TurboFold(20)).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 88
Total TN 9456
Total FP 25
Total FP CONTRA 8
Total FP INCONS 15
Total FP COMP 2
Total FN 41
Total Scores
MCC 0.732
Average MCC ± 95% Confidence Intervals 0.755 ± 0.236
Sensitivity 0.682
Positive Predictive Value 0.793
Nr of predictions 5

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3ZEX_C 0.50 0.45 0.57 13 5351 11 3 7 1 16
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of TurboFold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 87
Total TN 9456
Total FP 30
Total FP CONTRA 6
Total FP INCONS 18
Total FP COMP 6
Total FN 42
Total Scores
MCC 0.724
Average MCC ± 95% Confidence Intervals 0.744 ± 0.231
Sensitivity 0.674
Positive Predictive Value 0.784
Nr of predictions 5

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.