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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Multilign(seed) - scored higher in this pairwise comparison

  4. Performance of Vsfold4 - scored lower in this pairwise comparison

  5. Compile and download dataset for Multilign(seed) & Vsfold4 [.zip] - may take several seconds...


Overview

Metric Multilign(seed) Vsfold4
MCC 0.737 > 0.555
Average MCC ± 95% Confidence Intervals 0.694 ± 0.392 > 0.548 ± 0.409
Sensitivity 0.689 > 0.530
Positive Predictive Value 0.800 > 0.602
Total TP 104 > 80
Total TN 6580 > 6577
Total FP 28 < 56
Total FP CONTRA 7 < 9
Total FP INCONS 19 < 44
Total FP COMP 2 < 3
Total FN 47 < 71
P-value 0.0

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Performance plots


  1. Comparison of performance of Multilign(seed) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Multilign(seed) and Vsfold4).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Multilign(seed) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Multilign(seed) and Vsfold4).

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Performance of Multilign(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 104
Total TN 6580
Total FP 28
Total FP CONTRA 7
Total FP INCONS 19
Total FP COMP 2
Total FN 47
Total Scores
MCC 0.737
Average MCC ± 95% Confidence Intervals 0.694 ± 0.392
Sensitivity 0.689
Positive Predictive Value 0.800
Nr of predictions 6

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2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.97 0.94 1.00 17 340 0 0 0 0 1
2LC8_A -0.03 0.00 0.00 0 516 12 2 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.66 0.66 0.68 19 1505 9 4 5 0 10
3W3S_B 0.92 0.88 0.97 29 1959 2 0 1 1 4
4AOB_A 0.73 0.66 0.83 19 1414 5 1 3 1 10

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Performance of Vsfold4 - scored lower in this pairwise comparison

1. Total counts & total scores for Vsfold4

Total Base Pair Counts
Total TP 80
Total TN 6577
Total FP 56
Total FP CONTRA 9
Total FP INCONS 44
Total FP COMP 3
Total FN 71
Total Scores
MCC 0.555
Average MCC ± 95% Confidence Intervals 0.548 ± 0.409
Sensitivity 0.530
Positive Predictive Value 0.602
Nr of predictions 6

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2. Individual counts for Vsfold4 [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.89 1.00 16 341 1 0 0 1 2
2LC8_A -0.03 0.00 0.00 0 515 13 0 13 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.23 0.24 0.24 7 1504 22 5 17 0 22
3W3S_B 0.74 0.70 0.79 23 1960 7 1 5 1 10
4AOB_A 0.50 0.48 0.54 14 1411 13 3 9 1 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.