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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(20) - scored higher in this pairwise comparison

  4. Performance of Mastr(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(20) & Mastr(seed) [.zip] - may take several seconds...


Overview

Metric Murlet(20) Mastr(seed)
MCC 0.693 > 0.000
Average MCC ± 95% Confidence Intervals 0.690 ± 0.070 > 0.000 ± 0.000
Sensitivity 0.594 > 0.000
Positive Predictive Value 0.815 > 0.000
Total TP 532 > 0
Total TN 92209 < 92862
Total FP 202 > 0
Total FP CONTRA 25 > 0
Total FP INCONS 96 > 0
Total FP COMP 81 > 0
Total FN 364 < 896
P-value 3.56938820447e-08

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Performance plots


  1. Comparison of performance of Murlet(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  2. Comparison of performance of Murlet(20) and Mastr(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(20) and Mastr(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(20) and Mastr(seed)).

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Performance of Murlet(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(20)

Total Base Pair Counts
Total TP 532
Total TN 92209
Total FP 202
Total FP CONTRA 25
Total FP INCONS 96
Total FP COMP 81
Total FN 364
Total Scores
MCC 0.693
Average MCC ± 95% Confidence Intervals 0.690 ± 0.070
Sensitivity 0.594
Positive Predictive Value 0.815
Nr of predictions 34

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2. Individual counts for Murlet(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.70 0.50 1.00 5 169 0 0 0 0 5
2L94_A 0.51 0.50 0.56 9 341 8 0 7 1 9
2WRQ_Y 0.63 0.67 0.60 6 1142 13 1 3 9 3
2XKV_B 0.60 0.36 1.00 4 1831 3 0 0 3 7
2XQD_Y 0.88 0.86 0.90 18 1109 3 0 2 1 3
2XXA_G 0.44 0.20 1.00 7 2038 0 0 0 0 28
3A2K_C 0.88 0.86 0.90 19 1087 2 0 2 0 3
3AMU_B 0.89 0.89 0.89 17 1138 4 0 2 2 2
3G4S_9 0.85 0.77 0.95 20 2715 5 0 1 4 6
3GX2_A 0.73 0.54 1.00 15 1434 1 0 0 1 13
3IVN_B 0.80 0.65 1.00 15 888 0 0 0 0 8
3IZ4_A 0.46 0.33 0.66 31 25489 22 3 13 6 64
3IZF_C 0.88 0.83 0.94 29 2609 5 0 2 3 6
3J20_0 0.65 0.62 0.68 13 1200 6 1 5 0 8
3J20_1 0.69 0.60 0.80 12 1097 4 0 3 1 8
3J2L_3 0.84 0.74 0.96 25 2994 4 0 1 3 9
3JYV_7 0.84 0.80 0.89 16 1093 4 0 2 2 4
3JYX_4 0.72 0.75 0.69 9 4743 15 3 1 11 3
3JYX_3 0.76 0.73 0.79 11 2364 14 0 3 11 4
3LA5_A 0.80 0.64 1.00 16 938 0 0 0 0 9
3NPB_A 0.65 0.43 1.00 16 2262 2 0 0 2 21
3O58_2 1.00 1.00 1.00 31 2723 2 0 0 2 0
3O58_3 0.37 0.32 0.44 7 4748 13 4 5 4 15
3PDR_A 0.84 0.76 0.93 38 4799 3 1 2 0 12
3RKF_A 0.81 0.67 1.00 16 850 0 0 0 0 8
3SD1_A 0.82 0.83 0.83 24 1504 5 4 1 0 5
3ZEX_C 0.42 0.38 0.48 11 5351 16 2 10 4 18
3ZEX_D 0.90 0.86 0.94 30 2764 5 0 2 3 5
4A1C_3 0.72 0.59 0.88 22 2738 4 0 3 1 15
4A1C_2 0.22 0.25 0.20 5 4491 24 5 15 4 15
4AOB_A 0.87 0.76 1.00 22 1415 3 0 0 3 7
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.57 0.33 1.00 5 491 0 0 0 0 10
4FRG_B 0.19 0.17 0.25 4 1186 12 1 11 0 20

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Performance of Mastr(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Mastr(seed)

Total Base Pair Counts
Total TP 0
Total TN 92862
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 896
Total Scores
MCC 0.000
Average MCC ± 95% Confidence Intervals 0.000 ± 0.000
Sensitivity 0.000
Positive Predictive Value 0.000
Nr of predictions 34

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2. Individual counts for Mastr(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.00 0.00 0.00 0 174 0 0 0 0 10
2L94_A 0.00 0.00 0.00 0 357 0 0 0 0 18
2WRQ_Y 0.00 0.00 0.00 0 1152 0 0 0 0 9
2XKV_B 0.00 0.00 0.00 0 1835 0 0 0 0 11
2XQD_Y 0.00 0.00 0.00 0 1129 0 0 0 0 21
2XXA_G 0.00 0.00 0.00 0 2045 0 0 0 0 35
3A2K_C 0.00 0.00 0.00 0 1108 0 0 0 0 22
3AMU_B 0.00 0.00 0.00 0 1157 0 0 0 0 19
3G4S_9 0.00 0.00 0.00 0 2736 0 0 0 0 26
3GX2_A 0.00 0.00 0.00 0 1449 0 0 0 0 28
3IVN_B 0.00 0.00 0.00 0 903 0 0 0 0 23
3IZ4_A 0.00 0.00 0.00 0 25536 0 0 0 0 95
3IZF_C 0.00 0.00 0.00 0 2640 0 0 0 0 35
3J20_0 0.00 0.00 0.00 0 1219 0 0 0 0 21
3J20_1 0.00 0.00 0.00 0 1112 0 0 0 0 20
3J2L_3 0.00 0.00 0.00 0 3020 0 0 0 0 34
3JYV_7 0.00 0.00 0.00 0 1111 0 0 0 0 20
3JYX_4 0.00 0.00 0.00 0 4756 0 0 0 0 12
3JYX_3 0.00 0.00 0.00 0 2378 0 0 0 0 15
3LA5_A 0.00 0.00 0.00 0 954 0 0 0 0 25
3NPB_A 0.00 0.00 0.00 0 2278 0 0 0 0 37
3O58_2 0.00 0.00 0.00 0 2754 0 0 0 0 31
3O58_3 0.00 0.00 0.00 0 4764 0 0 0 0 22
3PDR_A 0.00 0.00 0.00 0 4840 0 0 0 0 50
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
3ZEX_D 0.00 0.00 0.00 0 2796 0 0 0 0 35
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.