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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Murlet(seed) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for Murlet(seed) & NanoFolder [.zip] - may take several seconds...


Overview

Metric Murlet(seed) NanoFolder
MCC 0.466 > 0.294
Average MCC ± 95% Confidence Intervals 0.466 ± 0.360 > 0.351 ± 0.333
Sensitivity 0.313 < 0.357
Positive Predictive Value 0.706 > 0.259
Total TP 36 < 41
Total TN 8915 > 8808
Total FP 16 < 135
Total FP CONTRA 0 < 27
Total FP INCONS 15 < 90
Total FP COMP 1 < 18
Total FN 79 > 74
P-value 0.0

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Performance plots


  1. Comparison of performance of Murlet(seed) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Murlet(seed) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Murlet(seed) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Murlet(seed) and NanoFolder).

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Performance of Murlet(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 36
Total TN 8915
Total FP 16
Total FP CONTRA 0
Total FP INCONS 15
Total FP COMP 1
Total FN 79
Total Scores
MCC 0.466
Average MCC ± 95% Confidence Intervals 0.466 ± 0.360
Sensitivity 0.313
Positive Predictive Value 0.706
Nr of predictions 5

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 0 12 0 18
3W3S_B 0.45 0.27 0.75 9 1977 3 0 3 0 24
4A1C_2 0.59 0.35 1.00 7 4509 0 0 0 0 13
4AOB_A 0.69 0.48 1.00 14 1423 1 0 0 1 15
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 41
Total TN 8808
Total FP 135
Total FP CONTRA 27
Total FP INCONS 90
Total FP COMP 18
Total FN 74
Total Scores
MCC 0.294
Average MCC ± 95% Confidence Intervals 0.351 ± 0.333
Sensitivity 0.357
Positive Predictive Value 0.259
Nr of predictions 5

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2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.54 0.61 0.50 11 506 11 1 10 0 7
3W3S_B 0.18 0.21 0.18 7 1949 34 2 31 1 26
4A1C_2 -0.01 0.00 0.00 0 4469 61 18 29 14 20
4AOB_A 0.39 0.41 0.39 12 1406 20 4 15 1 17
4ENC_A 0.66 0.73 0.61 11 478 9 2 5 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.