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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

  4. Performance of MaxExpect - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_2.0(seed) & MaxExpect [.zip] - may take several seconds...


Overview

Metric PETfold_2.0(seed) MaxExpect
MCC 0.866 > 0.845
Average MCC ± 95% Confidence Intervals 0.868 ± 0.471 > 0.839 ± 1.623
Sensitivity 0.845 < 0.862
Positive Predictive Value 0.891 > 0.833
Total TP 49 < 50
Total TN 4279 > 4274
Total FP 19 > 18
Total FP CONTRA 2 < 3
Total FP INCONS 4 < 7
Total FP COMP 13 > 8
Total FN 9 > 8
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_2.0(seed) and MaxExpect. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and MaxExpect).

  2. Comparison of performance of PETfold_2.0(seed) and MaxExpect. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and MaxExpect).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and MaxExpect. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and MaxExpect).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and MaxExpect. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and MaxExpect).

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Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 49
Total TN 4279
Total FP 19
Total FP CONTRA 2
Total FP INCONS 4
Total FP COMP 13
Total FN 9
Total Scores
MCC 0.866
Average MCC ± 95% Confidence Intervals 0.868 ± 0.471
Sensitivity 0.845
Positive Predictive Value 0.891
Nr of predictions 2

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.90 0.89 0.92 24 2630 14 0 2 12 3
3W1K_J 0.83 0.81 0.86 25 1649 5 2 2 1 6

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Performance of MaxExpect - scored lower in this pairwise comparison

1. Total counts & total scores for MaxExpect

Total Base Pair Counts
Total TP 50
Total TN 4274
Total FP 18
Total FP CONTRA 3
Total FP INCONS 7
Total FP COMP 8
Total FN 8
Total Scores
MCC 0.845
Average MCC ± 95% Confidence Intervals 0.839 ± 1.623
Sensitivity 0.862
Positive Predictive Value 0.833
Nr of predictions 2

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2. Individual counts for MaxExpect [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.71 0.74 0.69 20 2627 17 2 7 8 7
3W1K_J 0.97 0.97 0.97 30 1647 1 1 0 0 1

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.