CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

  4. Performance of Pknots - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_2.0(seed) & Pknots [.zip] - may take several seconds...


Overview

Metric PETfold_2.0(seed) Pknots
MCC 0.866 > 0.781
Average MCC ± 95% Confidence Intervals 0.868 ± 0.471 > 0.775 ± 2.440
Sensitivity 0.845 > 0.810
Positive Predictive Value 0.891 > 0.758
Total TP 49 > 47
Total TN 4279 > 4272
Total FP 19 < 21
Total FP CONTRA 2 < 4
Total FP INCONS 4 < 11
Total FP COMP 13 > 6
Total FN 9 < 11
P-value 0.0

^top




Performance plots


  1. Comparison of performance of PETfold_2.0(seed) and Pknots. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and Pknots).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and Pknots. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and Pknots).

^top





Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 49
Total TN 4279
Total FP 19
Total FP CONTRA 2
Total FP INCONS 4
Total FP COMP 13
Total FN 9
Total Scores
MCC 0.866
Average MCC ± 95% Confidence Intervals 0.868 ± 0.471
Sensitivity 0.845
Positive Predictive Value 0.891
Nr of predictions 2

^top



2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.90 0.89 0.92 24 2630 14 0 2 12 3
3W1K_J 0.83 0.81 0.86 25 1649 5 2 2 1 6

^top



Performance of Pknots - scored lower in this pairwise comparison

1. Total counts & total scores for Pknots

Total Base Pair Counts
Total TP 47
Total TN 4272
Total FP 21
Total FP CONTRA 4
Total FP INCONS 11
Total FP COMP 6
Total FN 11
Total Scores
MCC 0.781
Average MCC ± 95% Confidence Intervals 0.775 ± 2.440
Sensitivity 0.810
Positive Predictive Value 0.758
Nr of predictions 2

^top



2. Individual counts for Pknots [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.58 0.63 0.55 17 2625 20 3 11 6 10
3W1K_J 0.97 0.97 0.97 30 1647 1 1 0 0 1

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.