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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

  4. Performance of ProbKnot - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_2.0(seed) & ProbKnot [.zip] - may take several seconds...


Overview

Metric PETfold_2.0(seed) ProbKnot
MCC 0.866 > 0.848
Average MCC ± 95% Confidence Intervals 0.868 ± 0.471 > 0.845 ± 1.552
Sensitivity 0.845 < 0.879
Positive Predictive Value 0.891 > 0.823
Total TP 49 < 51
Total TN 4279 > 4272
Total FP 19 > 16
Total FP CONTRA 2 < 3
Total FP INCONS 4 < 8
Total FP COMP 13 > 5
Total FN 9 > 7
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_2.0(seed) and ProbKnot. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_2.0(seed) and ProbKnot).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_2.0(seed) and ProbKnot. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_2.0(seed) and ProbKnot).

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Performance of PETfold_2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_2.0(seed)

Total Base Pair Counts
Total TP 49
Total TN 4279
Total FP 19
Total FP CONTRA 2
Total FP INCONS 4
Total FP COMP 13
Total FN 9
Total Scores
MCC 0.866
Average MCC ± 95% Confidence Intervals 0.868 ± 0.471
Sensitivity 0.845
Positive Predictive Value 0.891
Nr of predictions 2

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2. Individual counts for PETfold_2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.90 0.89 0.92 24 2630 14 0 2 12 3
3W1K_J 0.83 0.81 0.86 25 1649 5 2 2 1 6

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Performance of ProbKnot - scored lower in this pairwise comparison

1. Total counts & total scores for ProbKnot

Total Base Pair Counts
Total TP 51
Total TN 4272
Total FP 16
Total FP CONTRA 3
Total FP INCONS 8
Total FP COMP 5
Total FN 7
Total Scores
MCC 0.848
Average MCC ± 95% Confidence Intervals 0.845 ± 1.552
Sensitivity 0.879
Positive Predictive Value 0.823
Nr of predictions 2

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2. Individual counts for ProbKnot [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J3V_B 0.72 0.78 0.68 21 2625 15 2 8 5 6
3W1K_J 0.97 0.97 0.97 30 1647 1 1 0 0 1

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.