Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
- Performance of RSpredict(seed)
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(20) & RSpredict(seed) [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(20) |
|
RSpredict(seed) |
|---|
| MCC |
0.792 |
>
|
0.365 |
| Average MCC ± 95% Confidence Intervals |
0.747
±
0.128
|
>
|
0.111
±
0.097
|
| Sensitivity |
0.763 |
>
|
0.220 |
| Positive Predictive Value |
0.823 |
>
|
0.609 |
| Total TP |
496 |
>
|
143 |
| Total TN |
199823 |
<
|
200191 |
| Total FP |
203 |
>
|
122 |
| Total FP CONTRA |
26 |
>
|
21 |
| Total FP INCONS |
81 |
>
|
71 |
| Total FP COMP |
96 |
>
|
30 |
| Total FN |
154 |
<
|
507 |
| P-value |
3.21671975982e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(20) and RSpredict(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and RSpredict(seed)).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and RSpredict(seed)).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(20) and RSpredict(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(20)
and RSpredict(seed)).
Performance of PETfold_pre2.0(20)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(20)
| Total Base Pair Counts |
|---|
| Total TP |
496 |
| Total TN |
199823 |
| Total FP |
203 |
| Total FP CONTRA |
26 |
| Total FP INCONS |
81 |
| Total FP COMP |
96 |
| Total FN |
154 |
| Total Scores |
|---|
| MCC |
0.792 |
| Average MCC ± 95% Confidence Intervals |
0.747
±
0.128
|
| Sensitivity |
0.763 |
| Positive Predictive Value |
0.823 |
| Nr of predictions |
18 |
Performance of RSpredict(seed)
- scored lower in this pairwise comparison
1. Total counts & total scores for RSpredict(seed)
| Total Base Pair Counts |
|---|
| Total TP |
143 |
| Total TN |
200191 |
| Total FP |
122 |
| Total FP CONTRA |
21 |
| Total FP INCONS |
71 |
| Total FP COMP |
30 |
| Total FN |
507 |
| Total Scores |
|---|
| MCC |
0.365 |
| Average MCC ± 95% Confidence Intervals |
0.111
±
0.097
|
| Sensitivity |
0.220 |
| Positive Predictive Value |
0.609 |
| Nr of predictions |
18 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
