CompaRNA - on-line benchmarks of RNA structure prediction methods

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Metric	PETfold_pre2.0(seed)		Afold
MCC	0.769	>	0.538
Average MCC ± 95% Confidence Intervals	0.714 ± 0.196	>	0.544 ± 0.283
Sensitivity	0.706	>	0.566
Positive Predictive Value	0.842	>	0.520
Total TP	96	>	77
Total TN	12929	>	12895
Total FP	42	<	106
Total FP CONTRA	4	<	21
Total FP INCONS	14	<	50
Total FP COMP	24	<	35
Total FN	40	<	59
P-value	0.0

Comparison of performance of PETfold_pre2.0(seed) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Afold).
Comparison of performance of PETfold_pre2.0(seed) and Afold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Afold).
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Afold).
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Afold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and Afold).

Total Scores
MCC	0.769
Average MCC ± 95% Confidence Intervals	0.714 ± 0.196
Sensitivity	0.706
Positive Predictive Value	0.842
Nr of predictions	6

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	0.41	0.33	0.55	6	517	5	0	5	0	12
3J3E_8	5_8S_rRNA links to Rfam database...	0.71	0.67	0.77	10	2729	8	1	2	5	5
3W3S_B	tRNA-Sec links to Rfam database...	0.80	0.73	0.89	24	1962	6	1	2	3	9
3ZEX_D	5S_rRNA links to Rfam database...	0.96	0.94	0.97	33	2762	6	0	1	5	2
4A1C_2	5_8S_rRNA links to Rfam database...	0.79	0.75	0.83	15	4498	12	1	2	9	5
4ENB_A	crcB links to Rfam database...	0.61	0.53	0.73	8	461	5	1	2	2	7

Total Scores
MCC	0.538
Average MCC ± 95% Confidence Intervals	0.544 ± 0.283
Sensitivity	0.566
Positive Predictive Value	0.520
Nr of predictions	6

RNA Chain	Rfam family	MCC	SENS	PPV	TP	TN	FP	FP CONTRA	FP INCONS	FP COMP	FN
2LC8_A	GP_knot1 links to Rfam database...	0.64	0.61	0.69	11	512	6	0	5	1	7
3J3E_8	5_8S_rRNA links to Rfam database...	0.26	0.33	0.21	5	2718	31	6	13	12	10
3W3S_B	tRNA-Sec links to Rfam database...	0.55	0.55	0.56	18	1957	15	4	10	1	15
3ZEX_D	5S_rRNA links to Rfam database...	0.82	0.77	0.87	27	2765	8	0	4	4	8
4A1C_2	5_8S_rRNA links to Rfam database...	0.19	0.25	0.15	5	4483	43	11	17	15	15
4ENB_A	crcB links to Rfam database...	0.81	0.73	0.92	11	460	3	0	1	2	4

Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.