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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for PETfold_pre2.0(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric PETfold_pre2.0(seed) CRWrnafold
MCC 0.816 > 0.636
Average MCC ± 95% Confidence Intervals 0.754 ± 0.203 > 0.632 ± 0.362
Sensitivity 0.761 > 0.639
Positive Predictive Value 0.881 > 0.643
Total TP 118 > 99
Total TN 11237 > 11217
Total FP 34 < 78
Total FP CONTRA 3 < 15
Total FP INCONS 13 < 40
Total FP COMP 18 < 23
Total FN 37 < 56
P-value 0.0

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Performance plots


  1. Comparison of performance of PETfold_pre2.0(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and CRWrnafold).

  2. Comparison of performance of PETfold_pre2.0(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and CRWrnafold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for PETfold_pre2.0(seed) and CRWrnafold).

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Performance of PETfold_pre2.0(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for PETfold_pre2.0(seed)

Total Base Pair Counts
Total TP 118
Total TN 11237
Total FP 34
Total FP CONTRA 3
Total FP INCONS 13
Total FP COMP 18
Total FN 37
Total Scores
MCC 0.816
Average MCC ± 95% Confidence Intervals 0.754 ± 0.203
Sensitivity 0.761
Positive Predictive Value 0.881
Nr of predictions 7

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2. Individual counts for PETfold_pre2.0(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.41 0.33 0.55 6 517 5 0 5 0 12
3J16_L 1.00 1.00 1.00 21 1138 1 0 0 1 0
4A1C_3 1.00 1.00 1.00 37 2726 2 0 0 2 0
4A1C_2 0.79 0.75 0.83 15 4498 12 1 2 9 5
4AOB_A 0.85 0.79 0.92 23 1412 4 0 2 2 6
4ENB_A 0.61 0.53 0.73 8 461 5 1 2 2 7
4ENC_A 0.61 0.53 0.73 8 485 5 1 2 2 7

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 99
Total TN 11217
Total FP 78
Total FP CONTRA 15
Total FP INCONS 40
Total FP COMP 23
Total FN 56
Total Scores
MCC 0.636
Average MCC ± 95% Confidence Intervals 0.632 ± 0.362
Sensitivity 0.639
Positive Predictive Value 0.643
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3J16_L 1.00 1.00 1.00 21 1138 0 0 0 0 0
4A1C_3 0.85 0.84 0.86 31 2727 7 0 5 2 6
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.