Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of Cylofold
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & Cylofold [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
Cylofold |
|---|
| MCC |
0.854 |
>
|
0.655 |
| Average MCC ± 95% Confidence Intervals |
0.819
±
0.103
|
>
|
0.673
±
0.133
|
| Sensitivity |
0.811 |
>
|
0.637 |
| Positive Predictive Value |
0.905 |
>
|
0.685 |
| Total TP |
257 |
>
|
202 |
| Total TN |
19478 |
>
|
19467 |
| Total FP |
71 |
<
|
118 |
| Total FP CONTRA |
6 |
<
|
32 |
| Total FP INCONS |
21 |
<
|
61 |
| Total FP COMP |
44 |
>
|
25 |
| Total FN |
60 |
<
|
115 |
| P-value |
1.55268413083e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Cylofold).
-
Comparison of performance of PETfold_pre2.0(seed) and Cylofold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Cylofold).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Cylofold).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Cylofold).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Cylofold).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Cylofold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Cylofold).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
257 |
| Total TN |
19478 |
| Total FP |
71 |
| Total FP CONTRA |
6 |
| Total FP INCONS |
21 |
| Total FP COMP |
44 |
| Total FN |
60 |
| Total Scores |
|---|
| MCC |
0.854 |
| Average MCC ± 95% Confidence Intervals |
0.819
±
0.103
|
| Sensitivity |
0.811 |
| Positive Predictive Value |
0.905 |
| Nr of predictions |
14 |
Performance of Cylofold
- scored lower in this pairwise comparison
1. Total counts & total scores for Cylofold
| Total Base Pair Counts |
|---|
| Total TP |
202 |
| Total TN |
19467 |
| Total FP |
118 |
| Total FP CONTRA |
32 |
| Total FP INCONS |
61 |
| Total FP COMP |
25 |
| Total FN |
115 |
| Total Scores |
|---|
| MCC |
0.655 |
| Average MCC ± 95% Confidence Intervals |
0.673
±
0.133
|
| Sensitivity |
0.637 |
| Positive Predictive Value |
0.685 |
| Nr of predictions |
14 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
