Table of contents:
- Overview
- Performance Plots
- Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
- Performance of Vsfold4
- scored lower in this pairwise comparison
- Compile and download dataset for PETfold_pre2.0(seed) & Vsfold4 [.zip] - may take several seconds...
Overview
| Metric |
PETfold_pre2.0(seed) |
|
Vsfold4 |
|---|
| MCC |
0.878 |
>
|
0.538 |
| Average MCC ± 95% Confidence Intervals |
0.842
±
0.070
|
>
|
0.551
±
0.121
|
| Sensitivity |
0.842 |
>
|
0.533 |
| Positive Predictive Value |
0.918 |
>
|
0.554 |
| Total TP |
438 |
>
|
277 |
| Total TN |
42600 |
>
|
42577 |
| Total FP |
132 |
<
|
289 |
| Total FP CONTRA |
12 |
<
|
64 |
| Total FP INCONS |
27 |
<
|
159 |
| Total FP COMP |
93 |
>
|
66 |
| Total FN |
82 |
<
|
243 |
| P-value |
5.1503931209e-08 |
Performance plots
-
Comparison of performance of PETfold_pre2.0(seed) and Vsfold4. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Vsfold4).
-
Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Vsfold4).
-
Comparison of average Matthews Correlation Coefficients (MCCs) for PETfold_pre2.0(seed) and Vsfold4. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data
(individual counts for PETfold_pre2.0(seed)
and Vsfold4).
Performance of PETfold_pre2.0(seed)
- scored higher in this pairwise comparison
1. Total counts & total scores for PETfold_pre2.0(seed)
| Total Base Pair Counts |
|---|
| Total TP |
438 |
| Total TN |
42600 |
| Total FP |
132 |
| Total FP CONTRA |
12 |
| Total FP INCONS |
27 |
| Total FP COMP |
93 |
| Total FN |
82 |
| Total Scores |
|---|
| MCC |
0.878 |
| Average MCC ± 95% Confidence Intervals |
0.842
±
0.070
|
| Sensitivity |
0.842 |
| Positive Predictive Value |
0.918 |
| Nr of predictions |
22 |
Performance of Vsfold4
- scored lower in this pairwise comparison
1. Total counts & total scores for Vsfold4
| Total Base Pair Counts |
|---|
| Total TP |
277 |
| Total TN |
42577 |
| Total FP |
289 |
| Total FP CONTRA |
64 |
| Total FP INCONS |
159 |
| Total FP COMP |
66 |
| Total FN |
243 |
| Total Scores |
|---|
| MCC |
0.538 |
| Average MCC ± 95% Confidence Intervals |
0.551
±
0.121
|
| Sensitivity |
0.533 |
| Positive Predictive Value |
0.554 |
| Nr of predictions |
22 |
Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based
on the paper by Gardener & Giegerich, 2004.
| 
