CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt Carnac(seed)
MCC 0.534 > 0.126
Average MCC ± 95% Confidence Intervals 0.549 ± 0.187 > 0.047 ± 0.105
Sensitivity 0.512 > 0.016
Positive Predictive Value 0.567 < 1.000
Total TP 127 > 4
Total TN 20401 < 20621
Total FP 122 > 0
Total FP CONTRA 34 > 0
Total FP INCONS 63 > 0
Total FP COMP 25 > 0
Total FN 121 < 244
P-value 1.5677163434e-08

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Performance plots


  1. Comparison of performance of RNASLOpt and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  2. Comparison of performance of RNASLOpt and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and Carnac(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 127
Total TN 20401
Total FP 122
Total FP CONTRA 34
Total FP INCONS 63
Total FP COMP 25
Total FN 121
Total Scores
MCC 0.534
Average MCC ± 95% Confidence Intervals 0.549 ± 0.187
Sensitivity 0.512
Positive Predictive Value 0.567
Nr of predictions 10

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
3W3S_B 0.90 0.85 0.97 28 1960 2 0 1 1 5
3ZEX_C 0.32 0.34 0.31 10 5342 36 8 14 14 19
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12
4A1C_3 0.79 0.73 0.87 27 2732 5 0 4 1 10
4AOB_A 0.31 0.28 0.38 8 1416 13 3 10 0 21
4ENB_A 0.85 0.73 1.00 11 461 0 0 0 0 4
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6
4FRG_B 0.60 0.58 0.64 14 1180 8 3 5 0 10
4FRN_A 0.19 0.18 0.22 5 1825 18 6 12 0 23

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 4
Total TN 20621
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 244
Total Scores
MCC 0.126
Average MCC ± 95% Confidence Intervals 0.047 ± 0.105
Sensitivity 0.016
Positive Predictive Value 1.000
Nr of predictions 10

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.47 0.22 1.00 4 524 0 0 0 0 14
3W3S_B 0.00 0.00 0.00 0 1989 0 0 0 0 33
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24
4FRN_A 0.00 0.00 0.00 0 1848 0 0 0 0 28

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.