CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASLOpt - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASLOpt & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric RNASLOpt RNASampler(seed)
MCC 0.511 > 0.371
Average MCC ± 95% Confidence Intervals 0.504 ± 0.443 > 0.341 ± 0.418
Sensitivity 0.530 > 0.290
Positive Predictive Value 0.500 > 0.483
Total TP 53 > 29
Total TN 12301 < 12347
Total FP 77 > 45
Total FP CONTRA 21 > 6
Total FP INCONS 32 > 25
Total FP COMP 24 > 14
Total FN 47 < 71
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASLOpt and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  2. Comparison of performance of RNASLOpt and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASLOpt and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASLOpt and RNASampler(seed)).

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Performance of RNASLOpt - scored higher in this pairwise comparison

1. Total counts & total scores for RNASLOpt

Total Base Pair Counts
Total TP 53
Total TN 12301
Total FP 77
Total FP CONTRA 21
Total FP INCONS 32
Total FP COMP 24
Total FN 47
Total Scores
MCC 0.511
Average MCC ± 95% Confidence Intervals 0.504 ± 0.443
Sensitivity 0.530
Positive Predictive Value 0.500
Nr of predictions 4

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2. Individual counts for RNASLOpt [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.48 0.39 0.64 7 517 4 0 4 0 11
3W3S_B 0.90 0.85 0.97 28 1960 2 0 1 1 5
3ZEX_C 0.32 0.34 0.31 10 5342 36 8 14 14 19
4A1C_2 0.30 0.40 0.24 8 4482 35 13 13 9 12

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 29
Total TN 12347
Total FP 45
Total FP CONTRA 6
Total FP INCONS 25
Total FP COMP 14
Total FN 71
Total Scores
MCC 0.371
Average MCC ± 95% Confidence Intervals 0.341 ± 0.418
Sensitivity 0.290
Positive Predictive Value 0.483
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3W3S_B 0.60 0.36 1.00 12 1977 1 0 0 1 21
3ZEX_C 0.39 0.31 0.50 9 5356 14 2 7 5 20
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.