CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of Multilign(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & Multilign(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) Multilign(20)
MCC 0.683 > 0.667
Average MCC ± 95% Confidence Intervals 0.681 ± 0.337 < 0.698 ± 0.573
Sensitivity 0.593 < 0.703
Positive Predictive Value 0.794 > 0.640
Total TP 54 < 64
Total TN 7204 > 7172
Total FP 23 < 44
Total FP CONTRA 4 < 13
Total FP INCONS 10 < 23
Total FP COMP 9 > 8
Total FN 37 > 27
P-value 0.0

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Performance plots


  1. Comparison of performance of RNASampler(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(20)).

  2. Comparison of performance of RNASampler(seed) and Multilign(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and Multilign(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and Multilign(20)).

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Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 54
Total TN 7204
Total FP 23
Total FP CONTRA 4
Total FP INCONS 10
Total FP COMP 9
Total FN 37
Total Scores
MCC 0.683
Average MCC ± 95% Confidence Intervals 0.681 ± 0.337
Sensitivity 0.593
Positive Predictive Value 0.794
Nr of predictions 4

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Performance of Multilign(20) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(20)

Total Base Pair Counts
Total TP 64
Total TN 7172
Total FP 44
Total FP CONTRA 13
Total FP INCONS 23
Total FP COMP 8
Total FN 27
Total Scores
MCC 0.667
Average MCC ± 95% Confidence Intervals 0.698 ± 0.573
Sensitivity 0.703
Positive Predictive Value 0.640
Nr of predictions 4

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2. Individual counts for Multilign(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
3RKF_A 0.91 0.88 0.95 21 844 1 0 1 0 3
3SD1_A 0.68 0.69 0.69 20 1504 9 4 5 0 9
4A1C_2 0.20 0.25 0.16 5 4485 33 9 17 7 15

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.