CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNASampler(seed) - scored higher in this pairwise comparison

  4. Performance of PPfold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNASampler(seed) & PPfold(20) [.zip] - may take several seconds...


Overview

Metric RNASampler(seed) PPfold(20)
MCC 0.617 > 0.609
Average MCC ± 95% Confidence Intervals 0.623 ± 0.279 > 0.597 ± 0.327
Sensitivity 0.525 < 0.533
Positive Predictive Value 0.733 > 0.703
Total TP 63 < 64
Total TN 12560 > 12555
Total FP 37 > 35
Total FP CONTRA 6 > 3
Total FP INCONS 17 < 24
Total FP COMP 14 > 8
Total FN 57 > 56
P-value 0.0

^top




Performance plots


  1. Comparison of performance of RNASampler(seed) and PPfold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

  2. Comparison of performance of RNASampler(seed) and PPfold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and PPfold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNASampler(seed) and PPfold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNASampler(seed) and PPfold(20)).

^top





Performance of RNASampler(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 63
Total TN 12560
Total FP 37
Total FP CONTRA 6
Total FP INCONS 17
Total FP COMP 14
Total FN 57
Total Scores
MCC 0.617
Average MCC ± 95% Confidence Intervals 0.623 ± 0.279
Sensitivity 0.525
Positive Predictive Value 0.733
Nr of predictions 5

^top



2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
3ZEX_C 0.39 0.31 0.50 9 5356 14 2 7 5 20
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

^top



Performance of PPfold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for PPfold(20)

Total Base Pair Counts
Total TP 64
Total TN 12555
Total FP 35
Total FP CONTRA 3
Total FP INCONS 24
Total FP COMP 8
Total FN 56
Total Scores
MCC 0.609
Average MCC ± 95% Confidence Intervals 0.597 ± 0.327
Sensitivity 0.533
Positive Predictive Value 0.703
Nr of predictions 5

^top



2. Individual counts for PPfold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.66 0.50 0.90 9 347 1 0 1 0 9
3RKF_A 0.86 0.79 0.95 19 846 1 0 1 0 5
3SD1_A 0.81 0.76 0.88 22 1508 3 2 1 0 7
3ZEX_C 0.38 0.31 0.47 9 5355 14 0 10 4 20
4A1C_2 0.27 0.25 0.29 5 4499 16 1 11 4 15

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.