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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(20) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(20) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNAalifold(20) CRWrnafold
MCC 0.735 > 0.668
Average MCC ± 95% Confidence Intervals 0.706 ± 0.253 > 0.692 ± 0.219
Sensitivity 0.677 < 0.683
Positive Predictive Value 0.804 > 0.663
Total TP 111 < 112
Total TN 12236 > 12205
Total FP 33 < 83
Total FP CONTRA 9 < 18
Total FP INCONS 18 < 39
Total FP COMP 6 < 26
Total FN 53 > 52
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(20) and CRWrnafold).

  2. Comparison of performance of RNAalifold(20) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(20) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(20) and CRWrnafold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(20) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(20) and CRWrnafold).

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Performance of RNAalifold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 111
Total TN 12236
Total FP 33
Total FP CONTRA 9
Total FP INCONS 18
Total FP COMP 6
Total FN 53
Total Scores
MCC 0.735
Average MCC ± 95% Confidence Intervals 0.706 ± 0.253
Sensitivity 0.677
Positive Predictive Value 0.804
Nr of predictions 7

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 1.00 1.00 1.00 19 1138 2 0 0 2 0
3SD1_A 0.84 0.86 0.83 25 1503 5 4 1 0 4
4A1C_3 0.90 0.84 0.97 31 2731 1 0 1 0 6
4A1C_2 0.22 0.25 0.19 5 4490 23 5 16 2 15
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 112
Total TN 12205
Total FP 83
Total FP CONTRA 18
Total FP INCONS 39
Total FP COMP 26
Total FN 52
Total Scores
MCC 0.668
Average MCC ± 95% Confidence Intervals 0.692 ± 0.219
Sensitivity 0.683
Positive Predictive Value 0.663
Nr of predictions 7

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3AMU_B 0.77 0.79 0.75 15 1137 8 0 5 3 4
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_3 0.85 0.84 0.86 31 2727 7 0 5 2 6
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.