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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) CMfinder(20)
MCC 0.839 > 0.536
Average MCC ± 95% Confidence Intervals 0.839 ± > 0.536 ±
Sensitivity 0.708 > 0.292
Positive Predictive Value 1.000 = 1.000
Total TP 17 > 7
Total TN 1185 < 1195
Total FP 0 = 0
Total FP CONTRA 0 = 0
Total FP INCONS 0 = 0
Total FP COMP 0 = 0
Total FN 7 < 17
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CMfinder(20)).

  2. Comparison of performance of RNAalifold(seed) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CMfinder(20)).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 17
Total TN 1185
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 7
Total Scores
MCC 0.839
Average MCC ± 95% Confidence Intervals 0.839 ±
Sensitivity 0.708
Positive Predictive Value 1.000
Nr of predictions 1

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4FRG_B

AdoCbl-variant links to Rfam database...

0.84 0.71 1.00 17 1185 0 0 0 0 7

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 7
Total TN 1195
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 17
Total Scores
MCC 0.536
Average MCC ± 95% Confidence Intervals 0.536 ±
Sensitivity 0.292
Positive Predictive Value 1.000
Nr of predictions 1

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
4FRG_B

AdoCbl-variant links to Rfam database...

0.54 0.29 1.00 7 1195 0 0 0 0 17

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.

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