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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAalifold(seed) - scored higher in this pairwise comparison

  4. Performance of CRWrnafold - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAalifold(seed) & CRWrnafold [.zip] - may take several seconds...


Overview

Metric RNAalifold(seed) CRWrnafold
MCC 0.582 > 0.513
Average MCC ± 95% Confidence Intervals 0.546 ± 0.318 > 0.533 ± 0.387
Sensitivity 0.437 < 0.524
Positive Predictive Value 0.786 > 0.516
Total TP 55 < 66
Total TN 8912 > 8854
Total FP 19 < 83
Total FP CONTRA 2 < 21
Total FP INCONS 13 < 41
Total FP COMP 4 < 21
Total FN 71 > 60
P-value 0.0

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Performance plots


  1. Comparison of performance of RNAalifold(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

  2. Comparison of performance of RNAalifold(seed) and CRWrnafold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAalifold(seed) and CRWrnafold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAalifold(seed) and CRWrnafold).

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Performance of RNAalifold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for RNAalifold(seed)

Total Base Pair Counts
Total TP 55
Total TN 8912
Total FP 19
Total FP CONTRA 2
Total FP INCONS 13
Total FP COMP 4
Total FN 71
Total Scores
MCC 0.582
Average MCC ± 95% Confidence Intervals 0.546 ± 0.318
Sensitivity 0.437
Positive Predictive Value 0.786
Nr of predictions 6

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2. Individual counts for RNAalifold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 516 12 0 12 0 18
3SD1_A 0.70 0.59 0.85 17 1513 3 2 1 0 12
4A1C_2 0.50 0.25 1.00 5 4511 2 0 0 2 15
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Performance of CRWrnafold - scored lower in this pairwise comparison

1. Total counts & total scores for CRWrnafold

Total Base Pair Counts
Total TP 66
Total TN 8854
Total FP 83
Total FP CONTRA 21
Total FP INCONS 41
Total FP COMP 21
Total FN 60
Total Scores
MCC 0.513
Average MCC ± 95% Confidence Intervals 0.533 ± 0.387
Sensitivity 0.524
Positive Predictive Value 0.516
Nr of predictions 6

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2. Individual counts for CRWrnafold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3SD1_A 0.63 0.66 0.61 19 1502 12 6 6 0 10
4A1C_2 0.19 0.25 0.15 5 4483 44 8 20 16 15
4AOB_A 0.71 0.69 0.74 20 1410 8 4 3 1 9
4ENB_A 0.85 0.73 1.00 11 461 2 0 0 2 4
4ENC_A 0.85 0.73 1.00 11 485 2 0 0 2 4

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.