CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of RNAshapes - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for RNAshapes & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric RNAshapes CMfinder(20)
MCC 0.659 > 0.652
Average MCC ± 95% Confidence Intervals 0.627 ± 0.365 < 0.662 ± 0.224
Sensitivity 0.667 > 0.518
Positive Predictive Value 0.661 < 0.831
Total TP 76 > 59
Total TN 8122 < 8166
Total FP 49 > 16
Total FP CONTRA 6 > 3
Total FP INCONS 33 > 9
Total FP COMP 10 > 4
Total FN 38 < 55
P-value 0.0

^top




Performance plots


  1. Comparison of performance of RNAshapes and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAshapes and CMfinder(20)).

  2. Comparison of performance of RNAshapes and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for RNAshapes and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAshapes and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAshapes and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for RNAshapes and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for RNAshapes and CMfinder(20)).

^top





Performance of RNAshapes - scored higher in this pairwise comparison

1. Total counts & total scores for RNAshapes

Total Base Pair Counts
Total TP 76
Total TN 8122
Total FP 49
Total FP CONTRA 6
Total FP INCONS 33
Total FP COMP 10
Total FN 38
Total Scores
MCC 0.659
Average MCC ± 95% Confidence Intervals 0.627 ± 0.365
Sensitivity 0.667
Positive Predictive Value 0.661
Nr of predictions 4

^top



2. Individual counts for RNAshapes [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.51 0.57 0.48 12 1194 14 3 10 1 9
3J2L_3 0.77 0.79 0.75 27 2984 14 1 8 5 7
3ZEX_D 0.86 0.80 0.93 28 2766 6 0 2 4 7
4FRG_B 0.36 0.38 0.38 9 1178 15 2 13 0 15

^top



Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 59
Total TN 8166
Total FP 16
Total FP CONTRA 3
Total FP INCONS 9
Total FP COMP 4
Total FN 55
Total Scores
MCC 0.652
Average MCC ± 95% Confidence Intervals 0.662 ± 0.224
Sensitivity 0.518
Positive Predictive Value 0.831
Nr of predictions 4

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.84 0.76 0.94 16 1202 2 1 0 1 5
3J2L_3 0.57 0.50 0.65 17 2994 11 2 7 2 17
3ZEX_D 0.70 0.54 0.90 19 2775 3 0 2 1 16
4FRG_B 0.54 0.29 1.00 7 1195 0 0 0 0 17

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.