CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Carnac(seed)
MCC 0.718 > 0.272
Average MCC ± 95% Confidence Intervals 0.724 ± 0.161 > 0.100 ± 0.226
Sensitivity 0.675 > 0.075
Positive Predictive Value 0.771 < 1.000
Total TP 162 > 18
Total TN 18806 < 18998
Total FP 65 > 1
Total FP CONTRA 13 > 0
Total FP INCONS 35 > 0
Total FP COMP 17 > 1
Total FN 78 < 222
P-value 1.3551590886e-08

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Performance plots


  1. Comparison of performance of TurboFold(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  2. Comparison of performance of TurboFold(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Carnac(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 162
Total TN 18806
Total FP 65
Total FP CONTRA 13
Total FP INCONS 35
Total FP COMP 17
Total FN 78
Total Scores
MCC 0.718
Average MCC ± 95% Confidence Intervals 0.724 ± 0.161
Sensitivity 0.675
Positive Predictive Value 0.771
Nr of predictions 10

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6
4FRG_B 0.93 0.88 1.00 21 1181 0 0 0 0 3

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 18
Total TN 18998
Total FP 1
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 1
Total FN 222
Total Scores
MCC 0.272
Average MCC ± 95% Confidence Intervals 0.100 ± 0.226
Sensitivity 0.075
Positive Predictive Value 1.000
Nr of predictions 10

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
3RKF_A 0.00 0.00 0.00 0 866 0 0 0 0 24
3SD1_A 0.00 0.00 0.00 0 1533 0 0 0 0 29
3ZEX_C 0.00 0.00 0.00 0 5374 0 0 0 0 29
4A1C_3 0.00 0.00 0.00 0 2763 0 0 0 0 37
4A1C_2 0.00 0.00 0.00 0 4516 0 0 0 0 20
4AOB_A 0.00 0.00 0.00 0 1437 0 0 0 0 29
4ENB_A 0.00 0.00 0.00 0 472 0 0 0 0 15
4ENC_A 0.00 0.00 0.00 0 496 0 0 0 0 15
4FRG_B 0.00 0.00 0.00 0 1202 0 0 0 0 24

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.