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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(20) - scored higher in this pairwise comparison

  4. Performance of Murlet(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(20) & Murlet(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(20) Murlet(seed)
MCC 0.691 > 0.543
Average MCC ± 95% Confidence Intervals 0.708 ± 0.179 > 0.550 ± 0.119
Sensitivity 0.645 > 0.360
Positive Predictive Value 0.749 < 0.830
Total TP 131 > 73
Total TN 16078 < 16165
Total FP 59 > 17
Total FP CONTRA 13 > 1
Total FP INCONS 31 > 14
Total FP COMP 15 > 2
Total FN 72 < 130
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  2. Comparison of performance of TurboFold(20) and Murlet(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(20) and Murlet(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(20) and Murlet(seed)).

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Performance of TurboFold(20) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(20)

Total Base Pair Counts
Total TP 131
Total TN 16078
Total FP 59
Total FP CONTRA 13
Total FP INCONS 31
Total FP COMP 15
Total FN 72
Total Scores
MCC 0.691
Average MCC ± 95% Confidence Intervals 0.708 ± 0.179
Sensitivity 0.645
Positive Predictive Value 0.749
Nr of predictions 9

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2. Individual counts for TurboFold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_2 0.22 0.25 0.21 5 4492 28 6 13 9 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6
4FRG_B 0.93 0.88 1.00 21 1181 0 0 0 0 3

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Performance of Murlet(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Murlet(seed)

Total Base Pair Counts
Total TP 73
Total TN 16165
Total FP 17
Total FP CONTRA 1
Total FP INCONS 14
Total FP COMP 2
Total FN 130
Total Scores
MCC 0.543
Average MCC ± 95% Confidence Intervals 0.550 ± 0.119
Sensitivity 0.360
Positive Predictive Value 0.830
Nr of predictions 9

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2. Individual counts for Murlet(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.57 0.39 0.88 7 349 2 0 1 1 11
3RKF_A 0.62 0.50 0.80 12 851 3 1 2 0 12
3SD1_A 0.56 0.38 0.85 11 1520 2 0 2 0 18
3ZEX_C 0.49 0.24 1.00 7 5367 0 0 0 0 22
4A1C_2 0.59 0.35 1.00 7 4509 0 0 0 0 13
4AOB_A 0.69 0.48 1.00 14 1423 1 0 0 1 15
4ENB_A 0.63 0.40 1.00 6 466 0 0 0 0 9
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9
4FRG_B 0.17 0.13 0.25 3 1190 9 0 9 0 21

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.