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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of MXScarna(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & MXScarna(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) MXScarna(20)
MCC 0.683 > 0.621
Average MCC ± 95% Confidence Intervals 0.697 ± 0.178 > 0.596 ± 0.184
Sensitivity 0.653 > 0.579
Positive Predictive Value 0.723 > 0.676
Total TP 141 > 125
Total TN 17619 < 17629
Total FP 74 < 91
Total FP CONTRA 16 < 19
Total FP INCONS 38 < 41
Total FP COMP 20 < 31
Total FN 75 < 91
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

  2. Comparison of performance of TurboFold(seed) and MXScarna(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and MXScarna(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and MXScarna(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 141
Total TN 17619
Total FP 74
Total FP CONTRA 16
Total FP INCONS 38
Total FP COMP 20
Total FN 75
Total Scores
MCC 0.683
Average MCC ± 95% Confidence Intervals 0.697 ± 0.178
Sensitivity 0.653
Positive Predictive Value 0.723
Nr of predictions 9

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of MXScarna(20) - scored lower in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 125
Total TN 17629
Total FP 91
Total FP CONTRA 19
Total FP INCONS 41
Total FP COMP 31
Total FN 91
Total Scores
MCC 0.621
Average MCC ± 95% Confidence Intervals 0.596 ± 0.184
Sensitivity 0.579
Positive Predictive Value 0.676
Nr of predictions 9

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.73 0.72 0.76 13 340 5 0 4 1 5
3RKF_A 0.86 0.75 1.00 18 848 0 0 0 0 6
3SD1_A 0.74 0.76 0.73 22 1503 9 6 2 1 7
3ZEX_C 0.35 0.31 0.41 9 5352 15 3 10 2 20
4A1C_3 0.80 0.78 0.83 29 2728 12 0 6 6 8
4A1C_2 0.22 0.25 0.21 5 4492 36 8 11 17 15
4AOB_A 0.68 0.69 0.69 20 1408 13 2 7 4 9
4ENB_A 0.29 0.13 0.67 2 469 1 0 1 0 13
4ENC_A 0.68 0.47 1.00 7 489 0 0 0 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.