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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of McQFold - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & McQFold [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) McQFold
MCC 0.647 > 0.616
Average MCC ± 95% Confidence Intervals 0.639 ± 0.205 < 0.679 ± 0.205
Sensitivity 0.615 < 0.622
Positive Predictive Value 0.691 > 0.620
Total TP 161 < 163
Total TN 19957 > 19927
Total FP 92 < 114
Total FP CONTRA 20 < 26
Total FP INCONS 52 < 74
Total FP COMP 20 > 14
Total FN 101 > 99
P-value 0.000969285703303

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Performance plots


  1. Comparison of performance of TurboFold(seed) and McQFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and McQFold).

  2. Comparison of performance of TurboFold(seed) and McQFold. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and McQFold).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and McQFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and McQFold).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and McQFold. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and McQFold).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 161
Total TN 19957
Total FP 92
Total FP CONTRA 20
Total FP INCONS 52
Total FP COMP 20
Total FN 101
Total Scores
MCC 0.647
Average MCC ± 95% Confidence Intervals 0.639 ± 0.205
Sensitivity 0.615
Positive Predictive Value 0.691
Nr of predictions 11

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6
4FRN_A 0.79 0.71 0.87 20 1825 3 1 2 0 8

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Performance of McQFold - scored lower in this pairwise comparison

1. Total counts & total scores for McQFold

Total Base Pair Counts
Total TP 163
Total TN 19927
Total FP 114
Total FP CONTRA 26
Total FP INCONS 74
Total FP COMP 14
Total FN 99
Total Scores
MCC 0.616
Average MCC ± 95% Confidence Intervals 0.679 ± 0.205
Sensitivity 0.622
Positive Predictive Value 0.620
Nr of predictions 11

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2. Individual counts for McQFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 1.00 1.00 1.00 18 339 1 0 0 1 0
2LC8_A 0.64 0.61 0.69 11 512 5 1 4 0 7
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.82 0.83 0.83 24 1504 5 1 4 0 5
3ZEX_C 0.33 0.34 0.32 10 5343 25 4 17 4 19
4A1C_3 0.28 0.30 0.28 11 2724 30 4 24 2 26
4A1C_2 0.19 0.25 0.16 5 4484 33 11 16 6 15
4AOB_A 0.50 0.48 0.54 14 1411 13 3 9 1 15
4ENB_A 1.00 1.00 1.00 15 457 0 0 0 0 0
4ENC_A 0.97 1.00 0.94 15 480 1 1 0 0 0
4FRN_A 0.82 0.71 0.95 20 1827 1 1 0 0 8

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.