CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of RNASampler(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & RNASampler(seed) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) RNASampler(seed)
MCC 0.547 > 0.543
Average MCC ± 95% Confidence Intervals 0.537 ± 0.412 > 0.515 ± 0.349
Sensitivity 0.543 > 0.457
Positive Predictive Value 0.560 < 0.656
Total TP 75 > 63
Total TN 13040 < 13078
Total FP 76 > 47
Total FP CONTRA 16 > 6
Total FP INCONS 43 > 27
Total FP COMP 17 > 14
Total FN 63 < 75
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and RNASampler(seed)).

  2. Comparison of performance of TurboFold(seed) and RNASampler(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and RNASampler(seed)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and RNASampler(seed)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and RNASampler(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and RNASampler(seed)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 75
Total TN 13040
Total FP 76
Total FP CONTRA 16
Total FP INCONS 43
Total FP COMP 17
Total FN 63
Total Scores
MCC 0.547
Average MCC ± 95% Confidence Intervals 0.537 ± 0.412
Sensitivity 0.543
Positive Predictive Value 0.560
Nr of predictions 6

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
2LC8_A -0.03 0.00 0.00 0 513 15 3 12 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15

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Performance of RNASampler(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for RNASampler(seed)

Total Base Pair Counts
Total TP 63
Total TN 13078
Total FP 47
Total FP CONTRA 6
Total FP INCONS 27
Total FP COMP 14
Total FN 75
Total Scores
MCC 0.543
Average MCC ± 95% Confidence Intervals 0.515 ± 0.349
Sensitivity 0.457
Positive Predictive Value 0.656
Nr of predictions 6

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2. Individual counts for RNASampler(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.70 0.56 0.91 10 346 2 0 1 1 8
2LC8_A -0.03 0.00 0.00 0 518 10 0 10 0 18
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.72 0.55 0.94 16 1516 1 0 1 0 13
3ZEX_C 0.39 0.31 0.50 9 5356 14 2 7 5 20
4A1C_2 0.40 0.40 0.40 8 4496 20 4 8 8 12

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.