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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of TurboFold(seed) - scored higher in this pairwise comparison

  4. Performance of RNAalifold(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for TurboFold(seed) & RNAalifold(20) [.zip] - may take several seconds...


Overview

Metric TurboFold(seed) RNAalifold(20)
MCC 0.683 > 0.663
Average MCC ± 95% Confidence Intervals 0.697 ± 0.178 > 0.637 ± 0.178
Sensitivity 0.653 > 0.602
Positive Predictive Value 0.723 < 0.739
Total TP 141 > 130
Total TN 17619 < 17638
Total FP 74 > 56
Total FP CONTRA 16 > 11
Total FP INCONS 38 > 35
Total FP COMP 20 > 10
Total FN 75 < 86
P-value 0.0

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Performance plots


  1. Comparison of performance of TurboFold(seed) and RNAalifold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and RNAalifold(20)).

  2. Comparison of performance of TurboFold(seed) and RNAalifold(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for TurboFold(seed) and RNAalifold(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and RNAalifold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and RNAalifold(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for TurboFold(seed) and RNAalifold(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for TurboFold(seed) and RNAalifold(20)).

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Performance of TurboFold(seed) - scored higher in this pairwise comparison

1. Total counts & total scores for TurboFold(seed)

Total Base Pair Counts
Total TP 141
Total TN 17619
Total FP 74
Total FP CONTRA 16
Total FP INCONS 38
Total FP COMP 20
Total FN 75
Total Scores
MCC 0.683
Average MCC ± 95% Confidence Intervals 0.697 ± 0.178
Sensitivity 0.653
Positive Predictive Value 0.723
Nr of predictions 9

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2. Individual counts for TurboFold(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.94 0.94 0.94 17 339 2 0 1 1 1
3RKF_A 0.91 0.83 1.00 20 846 0 0 0 0 4
3SD1_A 0.71 0.69 0.74 20 1506 7 2 5 0 9
3ZEX_C 0.49 0.45 0.54 13 5350 15 2 9 4 16
4A1C_3 0.86 0.84 0.89 31 2728 6 0 4 2 6
4A1C_2 0.20 0.25 0.17 5 4486 37 9 16 12 15
4AOB_A 0.67 0.59 0.77 17 1415 6 2 3 1 12
4ENB_A 0.77 0.60 1.00 9 463 0 0 0 0 6
4ENC_A 0.73 0.60 0.90 9 486 1 1 0 0 6

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Performance of RNAalifold(20) - scored lower in this pairwise comparison

1. Total counts & total scores for RNAalifold(20)

Total Base Pair Counts
Total TP 130
Total TN 17638
Total FP 56
Total FP CONTRA 11
Total FP INCONS 35
Total FP COMP 10
Total FN 86
Total Scores
MCC 0.663
Average MCC ± 95% Confidence Intervals 0.637 ± 0.178
Sensitivity 0.602
Positive Predictive Value 0.739
Nr of predictions 9

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2. Individual counts for RNAalifold(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2L94_A 0.51 0.50 0.56 9 341 8 0 7 1 9
3RKF_A 0.81 0.71 0.94 17 848 1 0 1 0 7
3SD1_A 0.84 0.86 0.83 25 1503 5 4 1 0 4
3ZEX_C 0.46 0.41 0.52 12 5351 16 2 9 5 17
4A1C_3 0.90 0.84 0.97 31 2731 1 0 1 0 6
4A1C_2 0.22 0.25 0.19 5 4490 23 5 16 2 15
4AOB_A 0.85 0.72 1.00 21 1416 2 0 0 2 8
4ENB_A 0.51 0.27 1.00 4 468 0 0 0 0 11
4ENC_A 0.63 0.40 1.00 6 490 0 0 0 0 9

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.