CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of CMfinder(20) - scored higher in this pairwise comparison

  4. Performance of NanoFolder - scored lower in this pairwise comparison

  5. Compile and download dataset for CMfinder(20) & NanoFolder [.zip] - may take several seconds...


Overview

Metric CMfinder(20) NanoFolder
MCC 0.507 > 0.183
Average MCC ± 95% Confidence Intervals 0.512 ± 0.826 > 0.185 ± 0.957
Sensitivity 0.353 > 0.186
Positive Predictive Value 0.735 > 0.190
Total TP 36 > 19
Total TN 14847 > 14796
Total FP 14 < 82
Total FP CONTRA 1 < 4
Total FP INCONS 12 < 77
Total FP COMP 1 = 1
Total FN 66 < 83
P-value 0.0

^top




Performance plots


  1. Comparison of performance of CMfinder(20) and NanoFolder. Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for CMfinder(20) and NanoFolder).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for CMfinder(20) and NanoFolder. The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for CMfinder(20) and NanoFolder).

^top





Performance of CMfinder(20) - scored higher in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 36
Total TN 14847
Total FP 14
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 1
Total FN 66
Total Scores
MCC 0.507
Average MCC ± 95% Confidence Intervals 0.512 ± 0.826
Sensitivity 0.353
Positive Predictive Value 0.735
Nr of predictions 2

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30

^top



Performance of NanoFolder - scored lower in this pairwise comparison

1. Total counts & total scores for NanoFolder

Total Base Pair Counts
Total TP 19
Total TN 14796
Total FP 82
Total FP CONTRA 4
Total FP INCONS 77
Total FP COMP 1
Total FN 83
Total Scores
MCC 0.183
Average MCC ± 95% Confidence Intervals 0.185 ± 0.957
Sensitivity 0.186
Positive Predictive Value 0.190
Nr of predictions 2

^top



2. Individual counts for NanoFolder [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J2L_3 0.11 0.11 0.12 6 7824 46 3 42 1 47
3ZEX_D 0.26 0.27 0.27 13 6972 36 1 35 0 36

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.