CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Carnac(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for Carnac(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric Carnac(20) CMfinder(20)
MCC 0.567 > 0.546
Average MCC ± 95% Confidence Intervals 0.561 ± 0.220 > 0.560 ± 0.222
Sensitivity 0.402 > 0.366
Positive Predictive Value 0.805 < 0.822
Total TP 66 > 60
Total TN 21150 < 21159
Total FP 18 > 15
Total FP CONTRA 0 < 1
Total FP INCONS 16 > 12
Total FP COMP 2 = 2
Total FN 98 < 104
P-value 0.0

^top




Performance plots


  1. Comparison of performance of Carnac(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Carnac(20) and CMfinder(20)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for Carnac(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Carnac(20) and CMfinder(20)).

^top





Performance of Carnac(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Carnac(20)

Total Base Pair Counts
Total TP 66
Total TN 21150
Total FP 18
Total FP CONTRA 0
Total FP INCONS 16
Total FP COMP 2
Total FN 98
Total Scores
MCC 0.567
Average MCC ± 95% Confidence Intervals 0.561 ± 0.220
Sensitivity 0.402
Positive Predictive Value 0.805
Nr of predictions 4

^top



2. Individual counts for Carnac(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.62 0.53 0.73 16 2828 7 0 6 1 14
3J2L_3 0.46 0.34 0.64 18 7847 11 0 10 1 35
3ZEX_D 0.73 0.53 1.00 26 6995 0 0 0 0 23
4FRG_B 0.43 0.19 1.00 6 3480 0 0 0 0 26

^top



Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

^top



2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.