CompaRNA - on-line benchmarks of RNA structure prediction methods
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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of Carnac(20) - scored higher in this pairwise comparison

  4. Performance of Carnac(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for Carnac(20) & Carnac(seed) [.zip] - may take several seconds...


Overview

Metric Carnac(20) Carnac(seed)
MCC 0.563 > 0.186
Average MCC ± 95% Confidence Intervals 0.490 ± 0.111 > 0.084 ± 0.120
Sensitivity 0.345 > 0.035
Positive Predictive Value 0.926 < 1.000
Total TP 286 > 29
Total TN 134743 < 135023
Total FP 38 > 0
Total FP CONTRA 3 > 0
Total FP INCONS 20 > 0
Total FP COMP 15 > 0
Total FN 544 < 801
P-value 5.06544643719e-08

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Performance plots


  1. Comparison of performance of Carnac(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  2. Comparison of performance of Carnac(20) and Carnac(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  3. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  4. Average Matthews Correlation Coefficients (MCC) with 95% confidence intervals (CIs) were plotted for different RNA families, for which at least 3 members were present in the benchmarking dataset. 'n' denotes the number of MCCs used to calculate the average and CI. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  5. Comparison of average Matthews Correlation Coefficients (MCCs) for Carnac(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

  6. Comparison of average Matthews Correlation Coefficients (MCCs) for Carnac(20) and Carnac(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for Carnac(20) and Carnac(seed)).

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Performance of Carnac(20) - scored higher in this pairwise comparison

1. Total counts & total scores for Carnac(20)

Total Base Pair Counts
Total TP 286
Total TN 134743
Total FP 38
Total FP CONTRA 3
Total FP INCONS 20
Total FP COMP 15
Total FN 544
Total Scores
MCC 0.563
Average MCC ± 95% Confidence Intervals 0.490 ± 0.111
Sensitivity 0.345
Positive Predictive Value 0.926
Nr of predictions 23

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2. Individual counts for Carnac(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.73 0.55 1.00 6 400 0 0 0 0 5
2L94_A 0.00 0.00 0.00 0 990 0 0 0 0 20
2XKV_B 0.32 0.10 1.00 2 4558 1 0 0 1 18
2XXA_G 0.27 0.07 1.00 3 5148 0 0 0 0 39
3GX2_A 0.57 0.33 1.00 13 4358 0 0 0 0 27
3IVN_B 0.78 0.61 1.00 19 2327 0 0 0 0 12
3IZF_C 0.73 0.56 0.97 30 6872 1 0 1 0 24
3JYX_4 0.46 0.21 1.00 7 12239 2 0 0 2 26
3JYX_3 0.64 0.56 0.75 15 6308 10 1 4 5 12
3LA5_A 0.78 0.62 1.00 21 2464 0 0 0 0 13
3NPB_A 0.44 0.20 1.00 9 7012 2 0 0 2 37
3O58_3 0.51 0.26 1.00 9 12394 0 0 0 0 26
3O58_2 0.83 0.71 0.96 27 7232 2 0 1 1 11
3PDR_A 0.62 0.40 0.97 29 12850 3 0 1 2 43
3RKF_A 0.76 0.59 1.00 20 2191 0 0 0 0 14
3SD1_A 0.60 0.38 0.94 16 3899 1 0 1 0 26
3ZEX_C 0.31 0.13 0.70 7 14186 3 1 2 0 45
4A1C_3 0.67 0.52 0.88 28 7108 4 0 4 0 26
4A1C_2 0.33 0.15 0.71 5 11774 3 0 2 1 28
4AOB_A 0.49 0.33 0.74 14 4352 6 1 4 1 28
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.43 0.19 1.00 6 3480 0 0 0 0 26

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Performance of Carnac(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Carnac(seed)

Total Base Pair Counts
Total TP 29
Total TN 135023
Total FP 0
Total FP CONTRA 0
Total FP INCONS 0
Total FP COMP 0
Total FN 801
Total Scores
MCC 0.186
Average MCC ± 95% Confidence Intervals 0.084 ± 0.120
Sensitivity 0.035
Positive Predictive Value 1.000
Nr of predictions 23

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2. Individual counts for Carnac(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2KDQ_B 0.95 0.91 1.00 10 396 0 0 0 0 1
2L94_A 0.97 0.95 1.00 19 971 0 0 0 0 1
2XKV_B 0.00 0.00 0.00 0 4560 0 0 0 0 20
2XXA_G 0.00 0.00 0.00 0 5151 0 0 0 0 42
3GX2_A 0.00 0.00 0.00 0 4371 0 0 0 0 40
3IVN_B 0.00 0.00 0.00 0 2346 0 0 0 0 31
3IZF_C 0.00 0.00 0.00 0 6903 0 0 0 0 54
3JYX_4 0.00 0.00 0.00 0 12246 0 0 0 0 33
3JYX_3 0.00 0.00 0.00 0 6328 0 0 0 0 27
3LA5_A 0.00 0.00 0.00 0 2485 0 0 0 0 34
3NPB_A 0.00 0.00 0.00 0 7021 0 0 0 0 46
3O58_3 0.00 0.00 0.00 0 12403 0 0 0 0 35
3O58_2 0.00 0.00 0.00 0 7260 0 0 0 0 38
3PDR_A 0.00 0.00 0.00 0 12880 0 0 0 0 72
3RKF_A 0.00 0.00 0.00 0 2211 0 0 0 0 34
3SD1_A 0.00 0.00 0.00 0 3916 0 0 0 0 42
3ZEX_C 0.00 0.00 0.00 0 14196 0 0 0 0 52
4A1C_3 0.00 0.00 0.00 0 7140 0 0 0 0 54
4A1C_2 0.00 0.00 0.00 0 11781 0 0 0 0 33
4AOB_A 0.00 0.00 0.00 0 4371 0 0 0 0 42
4ENB_A 0.00 0.00 0.00 0 1275 0 0 0 0 19
4ENC_A 0.00 0.00 0.00 0 1326 0 0 0 0 19
4FRG_B 0.00 0.00 0.00 0 3486 0 0 0 0 32

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.