CompaRNA - on-line benchmarks of RNA structure prediction methods
Home

Methods
Datasets
Rankings
RNA 2D Atlas

Help
FAQ

Contact us
RSS feeds
Twitter

Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of ContextFold - scored higher in this pairwise comparison

  4. Performance of Multilign(seed) - scored lower in this pairwise comparison

  5. Compile and download dataset for ContextFold & Multilign(seed) [.zip] - may take several seconds...


Overview

Metric ContextFold Multilign(seed)
MCC 0.517 > 0.477
Average MCC ± 95% Confidence Intervals 0.521 ± 0.219 > 0.414 ± 0.406
Sensitivity 0.421 > 0.358
Positive Predictive Value 0.640 < 0.642
Total TP 80 > 68
Total TN 29886 < 29905
Total FP 53 > 40
Total FP CONTRA 5 = 5
Total FP INCONS 40 > 33
Total FP COMP 8 > 2
Total FN 110 < 122
P-value 0.0

^top




Performance plots


  1. Comparison of performance of ContextFold and Multilign(seed). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for ContextFold and Multilign(seed)).

  2. Comparison of average Matthews Correlation Coefficients (MCCs) for ContextFold and Multilign(seed). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for ContextFold and Multilign(seed)).

^top





Performance of ContextFold - scored higher in this pairwise comparison

1. Total counts & total scores for ContextFold

Total Base Pair Counts
Total TP 80
Total TN 29886
Total FP 53
Total FP CONTRA 5
Total FP INCONS 40
Total FP COMP 8
Total FN 110
Total Scores
MCC 0.517
Average MCC ± 95% Confidence Intervals 0.521 ± 0.219
Sensitivity 0.421
Positive Predictive Value 0.640
Nr of predictions 5

^top



2. Individual counts for ContextFold [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A 0.55 0.50 0.63 10 1524 6 0 6 0 10
3W3S_B 0.79 0.70 0.90 28 4722 4 0 3 1 12
3ZEX_C 0.33 0.25 0.45 13 14167 22 1 15 6 39
4AOB_A 0.52 0.40 0.68 17 4346 9 1 7 1 25
4FRN_A 0.40 0.33 0.50 12 5127 12 3 9 0 24

^top



Performance of Multilign(seed) - scored lower in this pairwise comparison

1. Total counts & total scores for Multilign(seed)

Total Base Pair Counts
Total TP 68
Total TN 29905
Total FP 40
Total FP CONTRA 5
Total FP INCONS 33
Total FP COMP 2
Total FN 122
Total Scores
MCC 0.477
Average MCC ± 95% Confidence Intervals 0.414 ± 0.406
Sensitivity 0.358
Positive Predictive Value 0.642
Nr of predictions 5

^top



2. Individual counts for Multilign(seed) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
2LC8_A -0.01 0.00 0.00 0 1528 12 1 11 0 20
3W3S_B 0.84 0.73 0.97 29 4723 2 0 1 1 11
3ZEX_C 0.39 0.27 0.58 14 14172 10 3 7 0 38
4AOB_A 0.61 0.45 0.83 19 4348 5 0 4 1 23
4FRN_A 0.24 0.17 0.35 6 5134 11 1 10 0 30

^top


Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.