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Table of contents:

  1. Overview

  2. Performance Plots

  3. Performance of MXScarna(20) - scored higher in this pairwise comparison

  4. Performance of CMfinder(20) - scored lower in this pairwise comparison

  5. Compile and download dataset for MXScarna(20) & CMfinder(20) [.zip] - may take several seconds...


Overview

Metric MXScarna(20) CMfinder(20)
MCC 0.637 > 0.546
Average MCC ± 95% Confidence Intervals 0.647 ± 0.206 > 0.560 ± 0.222
Sensitivity 0.530 > 0.366
Positive Predictive Value 0.770 < 0.822
Total TP 87 > 60
Total TN 21119 < 21159
Total FP 28 > 15
Total FP CONTRA 5 > 1
Total FP INCONS 21 > 12
Total FP COMP 2 = 2
Total FN 77 < 104
P-value 0.0

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Performance plots


  1. Comparison of performance of MXScarna(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and CMfinder(20)).

  2. Comparison of performance of MXScarna(20) and CMfinder(20). Positive Predictive Value (PPV) is plotted against sensitivity. Each dot represents a single test of each method. See tables below for raw data (individual counts for MXScarna(20) and CMfinder(20)).

  3. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and CMfinder(20)).

  4. Comparison of average Matthews Correlation Coefficients (MCCs) for MXScarna(20) and CMfinder(20). The whiskers correspond to 95% confidence intervals (CIs). 'n' denotes the number of MCCs used to calculate average MCCs and CIs. See tables below for raw data (individual counts for MXScarna(20) and CMfinder(20)).

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Performance of MXScarna(20) - scored higher in this pairwise comparison

1. Total counts & total scores for MXScarna(20)

Total Base Pair Counts
Total TP 87
Total TN 21119
Total FP 28
Total FP CONTRA 5
Total FP INCONS 21
Total FP COMP 2
Total FN 77
Total Scores
MCC 0.637
Average MCC ± 95% Confidence Intervals 0.647 ± 0.206
Sensitivity 0.530
Positive Predictive Value 0.770
Nr of predictions 4

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2. Individual counts for MXScarna(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.82 0.67 1.00 20 2830 0 0 0 0 10
3J2L_3 0.54 0.42 0.71 22 7844 11 1 8 2 31
3ZEX_D 0.68 0.63 0.74 31 6979 11 2 9 0 18
4FRG_B 0.55 0.44 0.70 14 3466 6 2 4 0 18

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Performance of CMfinder(20) - scored lower in this pairwise comparison

1. Total counts & total scores for CMfinder(20)

Total Base Pair Counts
Total TP 60
Total TN 21159
Total FP 15
Total FP CONTRA 1
Total FP INCONS 12
Total FP COMP 2
Total FN 104
Total Scores
MCC 0.546
Average MCC ± 95% Confidence Intervals 0.560 ± 0.222
Sensitivity 0.366
Positive Predictive Value 0.822
Nr of predictions 4

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2. Individual counts for CMfinder(20) [ download as .csv ]

RNA Chain Rfam family MCC SENS PPV TP TN FP FP CONTRA FP INCONS FP COMP FN
3J20_0 0.75 0.57 1.00 17 2833 1 0 0 1 13
3J2L_3 0.45 0.32 0.63 17 7848 11 1 9 1 36
3ZEX_D 0.58 0.39 0.86 19 6999 3 0 3 0 30
4FRG_B 0.47 0.22 1.00 7 3479 0 0 0 0 25

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Matthews Correlation Coeffient, Sensitivity and Positive Predictive Value have been calculated based on the paper by Gardener & Giegerich, 2004.